Abstract
Sarcomas are relative rare malignant tumors arising from the mesenchymal tissue, which encompasses muscles, fat, bone, blood vessels, and fibrous or other supporting tissue [1]. An ulcer is a local defect or excavation of the surface of an organ or tissue characterized by a “full-thickness depth,” which implies that there are no sources for reepithelialization left in the center of the ulcer, and a “slow healing tendency” [2].
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Perisano C, et al. Misdiagnosis of soft tissue sarcomas of the lower limb associated with deep venous thrombosis: report of two cases and review of the literature. BMC Musculoskelet Disord. 2013;14:64.
Baker SR, et al. Epidemiology of chronic venous ulcers. Br J Surg. 1991;78:864–7.
Ilaslan H, et al. Clinical presentation and imaging of bone and soft-tissue sarcomas. Cleve Clin J Med. 2010;77 Suppl 1:S2–7.
What is sarcoma? http://www.sarcoma.org.uk/what-is-sarcoma
Simon MA, Springfield D. Surgery for Bone and Soft-Tissue Tumors. Philadelphia, PA: Lippincott-Raven; 1998. p. 198–200.
Burningham Z et al. The epidemiology of sarcoma. Clin Sarcoma Res. 2012. doi: 10.1186/2045-3329-2-14.
SEER*Stat Database: incidence – SEER 9 regs research Data, Nov 2010 Sub (1973–2008) < Katrina/Rita Population Adjustment > − Linked To County Attributes – Total U.S., 1969–2009 Counties, National Cancer Institute, DCCPS, Surveillance Research Program, Cancer Statistics Branch, released April 2011, based on the November 2010 submission. Surveillance, Epidemiology, and End Results (SEER) Program (http://www.seer.cancer.gov)
Howlader N, Noone AM, Krapcho M, Neyman N, Aminou R, Waldron W, Altekruse SF, Kosary CL, Ruhl J, Tatalovich Z, Cho H, Mariotto A, Eisner MP, Lewis DR, Chen HS, Feuer EJ, Cronin KA, Edwards BK, editors. SEER cancer statistics review, 1975–2008. National Cancer Institute. Bethesda; http://seer.cancer.gov/csr/1975_2008/, based on November 2010 SEER data submission, posted to the SEER web site. 2011.
Perisano C, et al. Soft tissue metastases in lung cancer: a review of the literature. Eur Rev Med Pharmacol Sci. 2012;16(14):1908–14.
Lookingbill DP, et al. Skin involvement as the presenting sign of internal carcinoma. J Am Acad Dermatol. 1990;22:19–26.
Ryan TJ. The epidemiology of leg ulcers. In: Westerhof W, editor. Leg Ulcers: Diagnosis and Treatment. Amsterdam: Elsevier Science Publishers BV; 1993.
Dowsett C. Malignant fungating wounds: assessment and management. Br J Nurs. 2002;7:394–400.
Clark J. Metronidazole gel in managing malodorous fungating wounds. Br J Nurs. 2002;11(6 Suppl):S54e–60.
Probst S, et al. Malignant fungating wounds: a survey of nurses’ clinical practice in Switzerland. Eur J Oncol Nurs. 2009;13:295–8.
Haisfield-Wolfe ME, Rund C. Malignant cutaneous wounds: a management protocol. Ostomy Wound Manage. 1997;43(1):56–60.
Mekkes JR, et al. Causes, investigation and treatment of leg ulceration. Br J Dermatol. 2003;148:388–401.
Khan AF, et al. Prevalence and presentation of chronic venous disease in Pakistan: a multicentre study. Phlebology. 2013. doi:10.1258/phleb.2012.011122.
Shmookler B et al. Bone and soft-tissue sarcomas: epidemiology, radiology, pathology and fundamentals of surgical treatment. Musculoskeletal cancer surgery. 2001. p. 3–35. doi: 10.1007/0-306-48407-2_1
Schwartz RA. Cutaneous metastatic disease. J Am Acad Dermatol. 1995;33:161–82.
Collier M. The assessment of patients with malignant fungating wounds – a holistic approach: part 1. Nurs Times. 1997;93(suppl):1–4.
Grocott P, Cowley S. The palliative management of fungating malignant wounds – generalising from multiple case study data using a system of reasoning. Int J Nurs Stud. 2001;38:533–45.
Naylor W. Assessment and management of pain in fungating wounds. Br J Nurs. 2001;10 Suppl 22:S33–6.
Eary JF, Conrad EU. Imaging in sarcoma. J Nucl Med. 2011. doi:10.2967/jnumed.111.092999.
White LM, Buckwalter KA. Technical considerations: CT and MR imaging in the postoperative orthopedic patient. Semin Musculoskelet Radiol. 2002;6:5–17.
Wu JS, Hochman MG. Soft-tissue tumors and tumorlike lesions: a systematic imaging approach. Radiology. 2009;253:297–316.
Chan WP. Magnetic resonance imaging of soft-tissue tumors of the extremities: a practical approach. World J Radiol. 2013;5(12):455–9.
Blodgett TM, et al. Issues, controversies, and clinical utility of combined PET/CT imaging: what is the interpreting physician facing? AJR Am J Roentgenol. 2005;184 Suppl 5:S138–45.
Grocott P. The management of fungating wounds. J Wound Care. 1999;8:232–4.
Maida V. Wound management in patients with advanced illness. Curr Opin Support Palliative Care. 2013. doi:10.1097/SPC0b013e32835c48e5.
Ferris FD, et al. Palliative wound care: managing chronic wounds across life’s continuum: a consensus statement from the International Palliative Wound Care Initiative. J Palliat Med. 2007;10:37–9.
Meaume S, et al. Neoplastic wounds and degenerescence. J Tissue Viability. 2013. doi:10.1016/j.jtv.2013.07.001.
Wafa H, Grimer RJ. Surgical options and outcomes in bone sarcoma. Expert Rev Anticancer Ther. 2006;6(2):239–48.
Gaston CL, et al. Is limb salvage surgery safe for bone sarcomas identified after a previous surgical procedure? Bone Joint J. 2014;96-B(5):665–72.
Papagelopoulos PJ, et al. Current concepts for management of soft tissue sarcomas of the extremities. J Surg Orthop Adv. 2008;17:204–15.
Daigeler A, et al. Proximal major limb amputations: a retrospective analysis of 45 oncological cases. World J Surg Oncol. 2009;7:15.
Dion N, Sim FH. The use of allografts in musculoskeletal oncology. Instr Course Lect. 2002;51:499–506.
Capanna R, et al. A new technique for reconstructions of large metadiaphyseal bone defects: a combined graft (allograft shell plus vascularized fibula). Orthop Traumatol. 1993;2:159–77.
Scoccianti G, et al. The use of osteo-articular allografts for reconstruction after resection of the distal radius for tumour. J Bone Joint Surg Br. 2010;92(12):1690–4.
Chang DW, Robb GL. Recent advances in reconstructive surgery for soft-tissue sarcomas. Curr Oncol Rep. 2000;2:495–501.
Chen CM, et al. Reconstruction of extremity long bone defects after sarcoma resection with vascularized fibula flaps: a 10-year review. Plast Reconstr Surg. 2007;119:915–24.
Kadam D. Limb salvage surgery. Indian J Plast Surg. 2013;46(2):265–74.
Saint-Cyr M, et al. Free tissue transfers and replantation. Plast Reconstruct Surg. 2012;130:858e.
Choudry UH, et al. The vascularized medial femoral condyle periosteal bone flap for the treatment of recalcitrant bony nonunions. Ann Plast Surg. 2008;60(2):174–80.
BC Cancer Agency. Malignant wound care guidelines. 2001; http://ww.bccancer.bc.ca.
Barton P, Parslow N. Caring for oncology wounds- management guidelines. 1998. http://www.worldwidewounds.com.
Cartwright A. Nutritional assessment as part of wound management. Nursing Times. 2002;98(44):62–3.
Collier M. Management of patients with fungating wounds. Nurs Stand. 2000;15(11):46–52.
“Care of malignant wounds” BCCA guidelines. 2004. http://www.bccancer.bc.ca/.
Seaman S. Dressing selection in chronic wound management. J Am Podiatr Med Assoc. 2002;92:24–33.
Ford-Dunn S. Use of vacuum assisted closure therapy in the palliation of a malignant wound. Palliat Med. 2006;20(4):477–8.
Cihoric N, et al. Clinically significant bleeding in incurable cancer patients: effectiveness of hemostatic radiotherapy. Radiat Oncol. 2012;7:132.
Lund-Nielsen B, et al. Qualitative bacteriology in malignant wounds – a prospective, randomized, clinical study compare the effect of honey and silver dressing. Ostomy Wound Manage. 2011;57:28–36.
Seaman S. Management of malignant fungating wounds in advanced cancer. Semin Oncol Nurs. 2006;22:185–93.
Kerihuel JC. Effect of activated charcoal dressings on healing outcomes of chronic wounds. J Wound Care. 2010;19(208):210–2, 214–5.
Ashford RFU, et al. Metronidazole in smelly tumours. Lancet. 1980;1:874–5.
Patterson DR, et al. Hypnotherapy as a treatment for pain in patients with burns: research and clinical considerations. J Burn Care Rehabil. 1987;8:263–8.
Greengrass RA, Duclas Jr R. Paravertebral blocks. Int Anesth Clin. 2012;50:56–73.
Krajnik M, et al. Potential uses of topical opioids in palliative care – report of 6 cases. Pain. 1999;80:121–5.
Flock P. Pilot study to determine the effectiveness of diamorphine gel to control pressure ulcer pain. J Pain Symptom Manage. 2003;25:547–54.
Vernassier C, et al. Study to determine the efficacy of topical morphine on painful chronic skin ulcers. J Wound Care. 2005;14:289–93.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2016 Springer India
About this chapter
Cite this chapter
Perisano, C., Maccauro, G. (2016). Sarcoma of Extremities Presenting as Ulceration. In: Khanna, A., Tiwary, S. (eds) Ulcers of the Lower Extremity. Springer, New Delhi. https://doi.org/10.1007/978-81-322-2635-2_25
Download citation
DOI: https://doi.org/10.1007/978-81-322-2635-2_25
Published:
Publisher Name: Springer, New Delhi
Print ISBN: 978-81-322-2633-8
Online ISBN: 978-81-322-2635-2
eBook Packages: MedicineMedicine (R0)