Abstract
Reporter genes have become an invaluable tool in studies of gene expression. Reporter gene technology is widely used to monitor the cellular events associated with signal transduction and gene expression. Based upon the splicing of transcriptional control elements to a variety of reporter genes (with easily measurable phenotypes), it “reports” the effects of a cascade of signaling events on gene expression inside cells. The principal advantage of these assays is their high sensitivity, reliability, convenience, and adaptability to large-scale measurements. They are widely used in biomedical and pharmaceutical research and also in molecular biology and biochemistry.
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Debnath, M., Prasad, G.B., Bisen, P.S. (2010). Reporter Gene. In: Molecular Diagnostics: Promises and Possibilities. Springer, Dordrecht. https://doi.org/10.1007/978-90-481-3261-4_5
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DOI: https://doi.org/10.1007/978-90-481-3261-4_5
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