Abstract
Continuing their study of the ethiopathogenesis of high myopia, the authors have determined serum Cortisol, testosterone, 17 β-estradiol, progesterone and urinary 17-KS and 17-OHCS, in a group of 55 males and 32 fecund females with high myopia (above — 10 D); the patients were strictly selected, excluding from the study all cases with signs of systemic disease.
The results showed in both sexes an increase in serum Cortisol level, as compared with a control group. Further there was a reduced serum testosterone in males, and an increased 17 β-estradiol in females, however only in the first half of the menstrual cycle. Progesteron showed no change.
The present results indicate a pathogenetic correlation between changes concerning glucocorticoid and sexual steroids and reduced resistance of the sclera in high myopia.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Avetisov, E. S., Winezkaja, M. I., Sawizkaja, N. F. Einige Stoffwechselwerte für saure Mukopolisaccharide bei der Myopie. Klin. Mbl. Augenheilk. 168: 750–754 (1976).
Balacco-Gabrieli, C. Indagine preliminare sui 17-chetosteroidi nella miopia degenerativa. Boll. Soc. It. Biol. Sper. 48: 241 (1972).
Balacco-Gabrieli, C. I 17-KS nelle miopia degenerativa. Boll. di Oculistica. 53: 195–203 (1974).
Balacco-Gabrieli, C, Scorcia, G., Asciano, F. Les mucopolysaccharides urinaires dans la myopie degenerative. Ann. d’Oculist. (Paris), 210: 147 (1977).
Balacco-Gabrieli, G., Santoro, G., Santoro, M., Abaticchio, G., Vavalle, G., Giorgino, R. Plasmatic and urinary steroids in the high myopia. Note I. Testosterone, 17-OH, 17-KS. Boll. Soc. Ital. Biol. Sper. 54: 975 (1978).
Balacco-Gabrieli, C., Santoro, G., Santoro, M., Scardapane, R., Tundo, R., Giorgino, R. Plasmatic and urinary steroids in the high myopia. Note 2. Cortisol, 17-OH, 17-KS (males). Boll. Soc. Ital. Biol. Sper. 54: 978 (1978).
Balacco-Gabrieli, C., Santoro, G., Santoro, M., Lattanzi, V., Di Gioia, C, Giorgino, R. Plasmatic and urinary steroids in the high myopia. Note 3. Cortisol, 17-OH, 17-KS (prolific females). Boll. Soc. Ital. Biol. Sper. 54: 981 (1978).
Balacco-Gabrieli, C, Santoro, G., Santoro, M., Bellizzi, M., Giorgino, R. Plasmatic and urinary steroids in the high myopia. Note 4. Progesterone, 17 β-estradiol, 17-OH, 17-KS. Boll. Soc. Ital. Biol. Sper. 54: 984 (1978).
Carnevalini, A., Givannini, E., Micheli, W., Mucci, M. P. Determinazione dell’ormone somatotropo (HGH) in soggetti giovani con miopia degenerativa. Relazione al 58° Congresso S.O.I. Roma (1977).
Digman, W.S., Voskhian, J., Assali, N. S. Effect of estrogens on renal hemodynamics and excretion of electrolytes in human subjects. J. Clin. Endocrinol. Metab. 16: 1032–1042 (1956).
Drekter, I. J., Heisler, A., Scism, G. R., Stern, S., Pearson, S., Mc Gavack, T. H. J. Clin. Endocr. Met. 12: 55 (1952).
Liu, H. C. A modified procedure for the estimation of total 17-Hydroxy-cortieosteroids (Porter Silberchromogens) in urine. Clin. Chem. 10: 103–115 (1964).
Preedy, J. R. K., Aitken, E. H. The effect of estrogen on water and electrolyte metabolism. J. Clin. Invest. 35: 423–429 (1956).
Author information
Authors and Affiliations
Editor information
Rights and permissions
Copyright information
© 1981 Dr W. Junk Publishers, The Hague
About this chapter
Cite this chapter
Balacco-Gabrieli, C., Tundo, R. (1981). A Study on the Effect of Some Steroid Hormones in Degenerative Myopia. In: Fledelius, H.C., Alsbirk, P.H., Goldschmidt, E. (eds) Third International Conference on Myopia Copenhagen, August 24–27, 1980. Documenta Ophthalmologica Proceedings Series, vol 28. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-8662-6_19
Download citation
DOI: https://doi.org/10.1007/978-94-009-8662-6_19
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-009-8664-0
Online ISBN: 978-94-009-8662-6
eBook Packages: Springer Book Archive