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CFD Applications for Drug Delivery

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Clinical and Biomedical Engineering in the Human Nose

Part of the book series: Biological and Medical Physics, Biomedical Engineering ((BIOMEDICAL))

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Abstract

This chapter provides the latest research trends in applications of CFD for investigating nasal drug delivery. Contributions include research and outcomes from the regulatory body, US Food Drug Administration on recent projects. Additionally, the chapter showcases the application of multiphase flow for capturing nasal spray drug delivery for improving olfactory targeting for nose-to-brain drug delivery, and nasal irrigation targeting the sinuses.

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Author information

Authors and Affiliations

  1. RMIT University, Melbourne, Australia

    Kendra Shrestha & Yidan Shang

  2. U.S. Food and Drug Administration, Silver Spring, USA

    Ross Walenga

  3. University of Massachusetts Lowell, Lowell, England

    Jinxiang Xi

  4. Auckland University of Technology, Auckland, New Zealand

    Hana Salati & David White

  5. University of Auckland, Auckland, New Zealand

    Jim Bartley

Authors
  1. Kendra Shrestha
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  2. Ross Walenga
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  3. Jinxiang Xi
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  4. Yidan Shang
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  5. Hana Salati
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  6. Jim Bartley
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  7. David White
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Corresponding author

Correspondence to Kendra Shrestha .

Editor information

Editors and Affiliations

  1. Mechanical and Automotive Engineering, School of Engineering, RMIT University, Bundoora, VIC, Australia

    Kiao Inthavong

  2. Sydney Medical School, University of Sydney, Sydney, NSW, Australia

    Narinder Singh

  3. Mechanical and Automotive Engineering, School of Engineering, RMIT University, Bundoora, VIC, Australia

    Eugene Wong

  4. Mechanical and Automotive Engineering, School of Engineering, RMIT University, Bundoora, VIC, Australia

    Jiyuan Tu

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Shrestha, K. et al. (2021). CFD Applications for Drug Delivery. In: Inthavong, K., Singh, N., Wong, E., Tu, J. (eds) Clinical and Biomedical Engineering in the Human Nose. Biological and Medical Physics, Biomedical Engineering. Springer, Singapore. https://doi.org/10.1007/978-981-15-6716-2_11

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  • DOI: https://doi.org/10.1007/978-981-15-6716-2_11

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