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Comparison Between Linked Color Imaging and Blue Laser Imaging for Improving the Visibility of Flat Colorectal Polyps: A Multicenter Pilot Study

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Abstract

Introduction

Linked color imaging (LCI) and blue laser imaging-bright (BLI-b) improve the visibility of gastrointestinal lesions. In this multicenter study, we compared the effects of LCI and BLI-b on the visibility of flat polyps with visibility scores and color difference (CD) values, including fast-withdrawal and large-monitor observation.

Methods

We recorded 120 videos of 40 consecutive flat polyps (2–20 mm), adenoma, and sessile serrated adenoma and polyp (SSA/P), using white light imaging (WLI), BLI-b, and LCI from July 2017 to December 2017. All videos were evaluated by eight endoscopists according to a published polyp visibility score of 4 (excellent) to 1 (poor). Additionally, 1.5 ×faster and 1.7 ×sized videos were evaluated. Moreover, we calculated the CD values for each polyp in three modes.

Results

The mean LCI scores (3.1 ± 0.9) were significantly higher than the WLI scores (2.5 ± 1.0, p < 0.001) but not significantly higher than the BLI-b scores (3.0 ± 1.0). The scores of faster videos on LCI (3.0 ± 1.1) were significantly higher than WLI (2.0 ± 1.0, p < 0.001) and BLI-b (2.8 ± 1.1, p = 0.03). The scores of larger-sized videos on LCI were not significantly higher than those of WLI or BLI-b. The CD value of LCI (18.0 ± 7.7) was higher than that of WLI (11.7 ± 7.0, p < 0.001), but was not significantly higher than that of BLI-b (16.6 ± 9.6). The CD value of LCI was significantly higher than that of BLI-b for adenoma, but the CD value of BLI-b was significantly higher than that of LCI for SSA/P.

Conclusions

The superiority of LCI to BLI-b was proven for the visibility of adenoma and fast observation.

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Acknowledgments

We thank Dr. Kewin Tien Ho Siah, Dr. Rafiz Abdul Rani, and all members of the Department of Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, for helping with this study.

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Authors and Affiliations

  1. Department of Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, 465 Kajii-cho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-8566, Japan

    Naohisa Yoshida, Ritsu Yasuda, Ken Inoue, Takaaki Murakami, Yutaka Inada & Yoshito Itoh

  2. Department of Gastroenterology, Fukuoka University Chikushi Hospital, Fukuoka, Japan

    Takashi Hisabe, Hiroshi Ishihara & Masaki Terasawa

  3. Department of Gastroenterology and Endoscopy, National Cancer Center Hospital East, Kashiwa, Chiba, Japan

    Hiroaki Ikematsu, Atsushi Inaba & Daiki Sato

  4. Endoscopy Division, National Cancer Center Hospital, Tokyo, Japan

    Hourin Cho, Mai Ego, Yusaku Tanaka & Yutaka Saito

Authors
  1. Naohisa Yoshida
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  2. Takashi Hisabe
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  3. Hiroaki Ikematsu
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  4. Hiroshi Ishihara
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  5. Masaki Terasawa
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  9. Mai Ego
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  10. Yusaku Tanaka
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  11. Ritsu Yasuda
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  13. Takaaki Murakami
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  14. Yutaka Inada
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  15. Yoshito Itoh
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  16. Yutaka Saito
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Corresponding author

Correspondence to Naohisa Yoshida.

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Conflict of interest

This study was performed by a research fund from Fujifilm (J162001222). Yoshito Itoh is affiliation with a donation-funded department from FUJIFILM Medical Co. Ltd. Naohisa Yoshida received a research grant from Fujifilm Co. The other authors have no conflicts of interest to declare.

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Three movies about white light imaging, linked color imaging, and blue laser imaging-bright for a non-polypoid lesion 18 mm, adenoma on the transverse colon (Figure 3a–3c) (MP4 21788 kb)

Three normal-speed movies and three 1.5 times faster movies about white light imaging, linked color imaging, and blue laser imaging for a polypoid lesion 5 mm, adenoma on the sigmoid colon (MP4 39774 kb)

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Yoshida, N., Hisabe, T., Ikematsu, H. et al. Comparison Between Linked Color Imaging and Blue Laser Imaging for Improving the Visibility of Flat Colorectal Polyps: A Multicenter Pilot Study. Dig Dis Sci 65, 2054–2062 (2020). https://doi.org/10.1007/s10620-019-05930-x

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  • DOI: https://doi.org/10.1007/s10620-019-05930-x

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