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Comparison of the performance of implantable cardioverter-defibrillator leads among manufacturers

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Abstract

Background

Leads are often considered the weakest link in implantable cardioverter-defibrillator (ICD) systems, and lead dysfunction is a major concern for ICD recipients. The aim of this study was to compare the lead performance from three different manufacturers.

Methods

We retrospectively reviewed consecutive patients who underwent ICD system implantation at Chiba University Hospital, Japan, between March 2008 and September 2017. The following leads were implanted in our center: Durata (St. Jude Medical, St. Paul, MN, USA, now Abbott) (n = 105), Linox and LinoxSmart (Biotronik, Berlin, Germany) (n = 66), and Sprint Quattro (Medtronic, Minneapolis, MN, USA) (n = 126).

Results

A total of 297 ICD leads were analyzed. Failure rates for Durata, Linox/LinoxSmart, and Sprint Quattro were 0.20%/patient year, 0.95%/patient year, and 1.84%/patient year, respectively, during a mean follow-up of 4.8, 6.4, and 3.0 years, respectively. The cumulative ICD lead survival probability was 98.9%, 100%, and 87.5%, after 5 years, respectively. The survival probability over the entire follow-up time as measured by the log-rank test was lower for Sprint Quattro leads than for either Durata (p = 0.011) or Linox/LinoxSmart (p = 0.028). The difference between Durata and Linox/LinoxSmart was not significant (p = 0.393).

Conclusions

In this single-center retrospective study, the performance of Sprint Quattro was lower than the performance of Linox/LinoxSmart and Durata leads. Large-scale, multi-center studies or manufacturer-independent registries may be necessary to confirm or reject self-reported survival probabilities from manufacturers’ product performance reports.

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Authors and Affiliations

  1. Department of Advanced Cardiorhythm Therapeutics, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8670, Japan

    Yusuke Kondo & Masahiro Nakano

  2. Department of Cardiovascular Medicine, Chiba University Graduate School of Medicine, Chiba, Japan

    Takatsugu Kajiyama, Miyo Nakano, Tomohiko Hayashi, Ryo Ito, Haruhiro Takahira & Yoshio Kobayashi

Authors
  1. Yusuke Kondo
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  2. Masahiro Nakano
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  3. Takatsugu Kajiyama
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  4. Miyo Nakano
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  5. Tomohiko Hayashi
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  8. Yoshio Kobayashi
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Corresponding author

Correspondence to Yusuke Kondo.

Ethics declarations

The investigation was approved by the local ethics committee.

Conflict of interest

Dr. Kondo received research grants from Abbott Japan, Biotronik Japan, and Boston Scientific. Dr. Kobayashi received research grants from Abbott Japan, Biotronik Japan, Boston Scientific, and Medtronic Japan. The other authors declare no conflicts of interest.

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Kondo, Y., Nakano, M., Kajiyama, T. et al. Comparison of the performance of implantable cardioverter-defibrillator leads among manufacturers. J Interv Card Electrophysiol 58, 133–139 (2020). https://doi.org/10.1007/s10840-019-00640-w

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  • DOI: https://doi.org/10.1007/s10840-019-00640-w

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