References
Nakanuma Y. Nodular regenerative hyperplasia of the liver: retrospective survey in autopsy series. J Clin Gastroenterol. 1990;12:460–5.
Wanless IR. Micronodular transformation (nodular regenerative hyperplasia) of the liver: a report of 64 cases among 2,500 autopsies and a new classification of benign hepatocellular nodules. Hepatology. 1990;11:787–97.
Rubbia-Brandt L, Lauwers GY, Wang H, Majno PE, Tanabe K, Zhu AX, et al. Sinusoidal obstruction syndrome and nodular regenerative hyperplasia are frequent oxaliplatin-associated liver lesions and partially prevented by bevacizumab in patients with hepatic colorectal metastasis. Histopathology. 2010;56:430–9.
Shin NY, Kim MJ, Lim JS, Park MS, Chung YE, Choi JY, et al. Accuracy of gadoxetic acid-enhanced magnetic resonance imaging for the diagnosis of sinusoidal obstruction syndrome in patients with chemotherapy-treated colorectal liver metastases. Eur Radiol. 2012;22:864–71.
Bioulac-Sage P, Laumonier H, Cubel G, Rossi JZ, Balabaud C. Hepatic resection for inflammatory hepatocellular adenomas: pathological identification of micronodules expressing inflammatory proteins. Liver Int. 2010;30:149–54.
Hubert C, Sempoux C, Horsmans Y, Rahier J, Humblet Y, Machiels JP, et al. Nodular regenerative hyperplasia: a deleterious consequence of chemotherapy for colorectal liver metastases? Liver Int. 2007;27:938–43.
Komori H, Beppu T, Baba Y, Horino K, Imsung C, Masuda T, et al. Histological liver injury and surgical outcome after FOLFOX followed by a hepatectomy for colorectal liver metastases in Japanese patients. Int J Clin Oncol. 2010 Jun;15(3):263–70.
Wicherts DA, de Haas RJ, Sebagh M, Ciacio O, Lévi F, Paule B, et al. Regenerative nodular hyperplasia of the liver related to chemotherapy: impact on outcome of liver surgery for colorectal metastases. Ann Surg Oncol. 2011;18:659–69.
Ribero D, Wang H, Donadon M, Zorzi D, Thomas MB, Eng C, et al. Bevacizumab improves pathologic response and protects against hepatic injury in patients treated with oxaliplatin based chemotherapy for colorectal liver metastases. Cancer. 2007;110:2761–7.
Donadon M, Di Tommaso L, Roncalli M, Torzilli G. Multiple focal nodular hyperplasias induced by oxaliplatin-based chemotherapy. World J Hepatol. 2013;5(6):340–4.
Choi JH, Won YW, Kim HS, Oh YH, Lim S, Kim HJ. Oxaliplatin-induced sinusoidal obstruction syndrome mimicking metastatic colon cancer in the liver. Oncol Lett. 2016;11(4):2861–4.
Arakawa Y, Shimada M, Utsunomya T, Imura S, Morine Y, Ikemoto T, et al. Oxaliplatin-related sinusoidal obstruction syndrome mimicking metastatic liver tumors. Hepatol Res. 2013;43(6):685–9.
Uchino K, Fujisawa M, Watanabe T, Endo Y, Nobuhisa T, Matsumoto Y, et al. Oxaliplatin-induced liver injury mimicking metastatic tumor on images: a case report. Jpn J Clin Oncol. 2013;43(10):1034–8.
Author information
Authors and Affiliations
Contributions
Chirag Jain prepared the first draft of the paper.
Asif Syed collected all the images and follow up of the patient for compiling the manuscript.
Nikhil Gupta contributed in the clinical management of the patient and also in correcting the draft of the manuscript.
Meenakshi Kambhoj prepared the pathology manuscript of the patient in the study.
Avinash Rao finalized the radiological findings and contributed significantly in the preparation of the manuscript.
Shivendra Singh finalized the manuscript and contributed significantly in editing the manuscript.
Corresponding author
Ethics declarations
Conflict of Interest
The authors declare that there are no conflicts of interest.
Additional information
Publisher’s Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Jain, C., Syed, A., Gupta, N. et al. Oxaliplatin-Induced Multiple Focal Nodular Hyperplasia Masquerading as Colorectal Liver Metastasis—Case Report and Review of Literature. J Gastrointest Canc 51, 628–630 (2020). https://doi.org/10.1007/s12029-019-00307-9
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12029-019-00307-9