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Peptide Materials for Smart Therapeutic Applications

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Abstract

Myriad peptides have been reported for utilization as key motives in design of smart therapeutic materials due to their capabilities for selective binding, self-assembly, and bioresponsiveness. In this review, we describe various therapeutic applications of peptides, their derivatives, and their assemblies by employing the bioresponsive characteristics. Peptide materials have been developed for specific targeting or deep tissue penetration. Amphiphilic peptides and their self-assembled materials also have been adopted for the development of therapeutic materials. Furthermore, triggered structural transformation of the self-assemblies of peptides in response to various stimuli in biological environments facilitates diverse therapeutic applications of peptide materials.

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Acknowledgments

This work was supported by the National Research Foundation of Korea (NRF) (NRF-2020R1A2C1013219). C.K. also thanks Inha University for support.

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  1. Department of Polymer Science and Engineering, Inha University, Incheon, 22212, Korea

    Jeonghun Lee & Chulhee Kim

  2. Program in Environmental and Polymer Engineering, Inha University, Incheon, 22212, Korea

    Chulhee Kim

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  1. Jeonghun Lee
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Lee, J., Kim, C. Peptide Materials for Smart Therapeutic Applications. Macromol. Res. 29, 2–14 (2021). https://doi.org/10.1007/s13233-021-9011-x

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