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Targeting Magnetic Nanoparticles in High Magnetic Fields for Drug Delivery Purposes

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Abstract

Biodegradable magnetic nanoparticles were synthesized using Poly(L-Lactic Acid) and magnetite nanoparticles (∼14 nm) at different dosages, and then these nanaoparticles (nanocomposites) and pure magnetic particles were targeted in external magnetic fields by changing the test parameters. The magnetic field test results showed that magnetic saturation, fluid speed, magnetic field distance and particle size were extremely effective for a magnetic guidance system that is needed for an effective drug delivery approach. Thus, it is assumed that such nanoparticles can carry drugs (chemotherapy) to be able to cure cancer tumors as well as many other diseases.

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Authors and Affiliations

  1. Fiber & Electro Optics Research Center, Bradley Department of Electrical and Computer Engineering, Virginia Tech, 106 Plantation Road, Blacksburg, VA, 24061, USA

    Ramazan Asmatulu & Richard.O. Claus

  2. Department of Chemistry, Virginia Tech, 2018 Hahn Hall, Blacksburg, VA, 24061, USA

    Judy S. Riffle & Michael Zalich

Authors
  1. Ramazan Asmatulu
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  2. Richard.O. Claus
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  3. Judy S. Riffle
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  4. Michael Zalich
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Asmatulu, R., Claus, R., Riffle, J.S. et al. Targeting Magnetic Nanoparticles in High Magnetic Fields for Drug Delivery Purposes. MRS Online Proceedings Library 820, 85–90 (2004). https://doi.org/10.1557/PROC-820-O3.8

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  • DOI: https://doi.org/10.1557/PROC-820-O3.8

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