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Leukocyte Adhesion to Endothelium

  • Chapter
Macrophages and Related Cells

Part of the book series: Blood Cell Biochemistry ((BLBI,volume 5))

Abstract

The recruitment of leukocytes from the blood is a prerequisite for their participation in inflammatory responses within the tissues. In the case of monocytes, a low level of emigration takes place under physiological conditions, but this is greatly increased in the inflammatory setting. An analysis of mechanisms of monocyte—endothelial cell (EC) adhesion is therefore of great relevance to understanding the pathophysiology of diverse acute and chronic inflammatory conditions as well as that of wound healing and tissue repair.

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Authors and Affiliations

  1. Department of Oral Medicine and Periodontology, The London Hospital Medical College, London, El 2AD, UK

    Martin H. Thornhill

  2. Rheumatology Unit, Department of Medicine, Royal Postgraduate Medical School, Hammersmith Hospital, London, W12 ONN, UK

    Dorian O. Haskard

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  1. Martin H. Thornhill
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  1. Imperial Cancer Research Fund Haemopoiesis Research Group, Department of Haematology, St. Bartholomew’s Hospital Medical College, EC1A 7BE, London, UK

    Michael A. Horton

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Thornhill, M.H., Haskard, D.O. (1993). Leukocyte Adhesion to Endothelium. In: Horton, M.A. (eds) Macrophages and Related Cells. Blood Cell Biochemistry, vol 5. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9534-9_15

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