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Triterpenoids with a Five-Membered a-Ring: Distribution in Nature, Transformations, Synthesis, and Biological Activity

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Chemistry of Natural Compounds Aims and scope

The literature on the distribution in nature, structural variations, isolation, identification, and biosynthesis issues of triterpenoids with a five-membered A-ring was reviewed. The principal trends in approaches to the synthesis of structural analogs of such compounds were discussed. Information on the biological activity of natural and semi-synthetic A-pentacyclic triterpenoids was presented.

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Acknowledgment

The work was sponsored by the RAS Presidium Program “Basic Science – Medicine” (Grant No. 12-R-3-1009) and a grant from the RFBR (No. 14-03-96007-r_ural-a).

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  1. Institute of Technical Chemistry, Ural Branch, Russian Academy of Sciences, 614013, Russia, Perm

    V. V. Grishko, I. A. Tolmacheva & A. V. Pereslavtseva

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Translated from Khimiya Prirodnykh Soedinenii, No. 1, January–February, 2015, pp. 5–24.

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Grishko, V.V., Tolmacheva, I.A. & Pereslavtseva, A.V. Triterpenoids with a Five-Membered a-Ring: Distribution in Nature, Transformations, Synthesis, and Biological Activity. Chem Nat Compd 51, 1–21 (2015). https://doi.org/10.1007/s10600-015-1193-z

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