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1-Hexadecyl-3-methylimidazolium Ionic Liquid as a New Cationic Surfactant for Separation of Phenolic Compounds by MEKC

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Abstract

The ionic liquid 1-hexadecyl-3-methylimidazolium bromide ([C16MIm]Br) has been used as a novel cationic surfactant for separation of phenolic compounds, including quinol, phloroglucinol, resorcinol, phenol, p-cresol, and m-nitrophenol, by micellar electrokinetic capillary chromatography (MEKC). The effects of buffer concentration and pH, concentration of [C16MIm]Br, and applied potential were studied. Use of the optimized buffer (25 mmol L−1 NaH2PO4), 10 mmol L−1 [C16MIm]Br, and an applied potential of −15 kV enables optimum separation with regard to resolution and migration time. The phenolic compounds were detected at 214 nm. The micelle of this long-alkyl-chain imidazolium ionic liquid acts as a pseudo-stationary phase in this MEKC separation.

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Acknowledgments

The first two authors contributed equally to this work. Financial support from the National Natural Science Foundation of China (nos. 20475058 and 20775084) is gratefully acknowledged. The authors thank Dr. Qinghua Zhang and Dr. Zuopeng Li for their generous help with the experiments.

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Authors and Affiliations

  1. Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, CAS, 730000, Lanzhou, China

    Jingang Niu, Hongdeng Qiu, Jing Li, Xia Liu & Shengxiang Jiang

  2. Graduate School of the Chinese Academy of Sciences, CAS, 100039, Beijing, China

    Jingang Niu & Jing Li

Authors
  1. Jingang Niu
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  2. Hongdeng Qiu
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  3. Jing Li
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  4. Xia Liu
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  5. Shengxiang Jiang
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Correspondence to Shengxiang Jiang.

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Niu, J., Qiu, H., Li, J. et al. 1-Hexadecyl-3-methylimidazolium Ionic Liquid as a New Cationic Surfactant for Separation of Phenolic Compounds by MEKC. Chroma 69, 1093–1096 (2009). https://doi.org/10.1365/s10337-009-1028-9

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