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Reactions of 5-dialkylamino-1,2,3-thiadiazole-4-carbaldehydes with amines as a method for the synthesis of 1,2,3-triazole-4-carbothioamides

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Abstract

A method for the synthesis of previously inaccessible 5-dialkylamino-substituted 1,2,3-thiadiazole-4-carbaldehydes was developed. Ring transformation in these compounds induced by primary aliphatic and aromatic amines, hydroxylamines, and N-substituted hydrazines resulted in the synthesis of a broad range of 1,2,3-triazole-4-carbothioamide.

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Authors and Affiliations

  1. Urals State Technical University, 19 ul. Mira, 620002 Ekaterinburg, Russian Federation, Russia

    T. V. Glukhareva, Yu. Yu. Morzherin, L. V. Dyudya, K. V. Malysheva & V. A. Bakulev

  2. N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, 9 prosp. akad. Lavrent"eva, 630090 Novosibirsk, Russian Federation, Russia

    A. V. Tkachev

  3. Department of Chemistry, Emory University, 1515, Pierce Drive, Atlanta GA, 30322, USA

    A. Padva

Authors
  1. T. V. Glukhareva
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  2. Yu. Yu. Morzherin
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  3. L. V. Dyudya
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  4. K. V. Malysheva
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  5. A. V. Tkachev
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  6. A. Padva
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  7. V. A. Bakulev
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Glukhareva, T.V., Morzherin, Y.Y., Dyudya, L.V. et al. Reactions of 5-dialkylamino-1,2,3-thiadiazole-4-carbaldehydes with amines as a method for the synthesis of 1,2,3-triazole-4-carbothioamides. Russian Chemical Bulletin 53, 1311–1317 (2004). https://doi.org/10.1023/B:RUCB.0000042292.19119.3d

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  • DOI: https://doi.org/10.1023/B:RUCB.0000042292.19119.3d

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