Collection

CRISPR/Cas-mediated gene editing to ensure product quality and plant performance

Submission status
Closed
Functional gene analysis gets a boost via the emergence of customised endonuclease platforms as transcription activator-like effector nucleases (TALEN) and clustered regularly interspaced short palindromic repeats (CRISPR). Due to the general use of the components, not only model plants can be manipulated. Never before has a technology allowed to make targeted knockouts and allele conversions with such precision in nearly all organisms tested. Meanwhile, the success stories include targeted knockout of single or multiple genes, base editing, prime editing, rearrangement of chromosomal segments and gene targeting. Genes can be activated or repressed, and genomic locations decorated with fluorescent probes. Genes can be epigenetically altered or modified by wide hybridisations. With all the progress, basic science can now be shifted to application. Plants can be made more resistant to pathogens and can be more efficient in nutrient uptake and product quality. Allergens can be removed and further processing positively influenced. As the number of reviews in the field of CRISPR-based technology is high, this topical article collection would like to focus on product quality and crop performance.

Editors

  • Tamas Dalmay Tamas Dalmay  &

    Tamas Dalmay

    Prof. Dalmay is a professor of RNA biology at the University of East Anglia. He is a molecular biologist with primary interests in RNA silencing. His research group uses molecular techniques to study short RNAs that regulate the expression of protein coding genes. The group’s research involves a variety of species including both plants and animals (Arabidopsis, tomato, mammals, chicken, etc.)

  • Götz Hensel Götz Hensel

    Götz Hensel

    Dr. Hensel is the Head of the Centre for Plant Genome Engineering associated with the Institute of Plant Biochemistry of Heinrich-Heine-Universität Düsseldorf. His research focus is on the targeted genome modification of crop plants. This includes classical transgenic approaches and the use of new methods of targeted mutagenesis, better known as CRISPR/Cas technology.

Articles (12 in this collection)