Summary
The inhibition of D-Amino Acid Oxidase by α-Keto Acid, product of the reaction with D-Amino Acid is described for the first time. Inhibition of the enzyme by α-Keto-γ-Methiolbutyric Acid (4-methylthio-2-oxobutanoic acid), product of the reaction with D-Methionine, was studied. From the results obtained it is deduced that inhibition is competitive with the substrate, the value of the inhibition constant being 1.85 10−3 M.
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Moreno, J.A., Catalán, J. & Galán, M.A. Inhibition of D-amino Acid Oxidase by α-Keto-γ-Methiolbutyric Acid, product of the reaction with D-Methionine. Biotechnol Lett 16, 843–848 (1994). https://doi.org/10.1007/BF00133965
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DOI: https://doi.org/10.1007/BF00133965