Abstract
We studied characteristics of ocular inflammation associated with yersinia infection in six children, three boys and three girls, ranging in age between 4 and 14 years. Four patients developed acute anterior uveitis with aqueous flare and cells, small keratic precipitates, cells in the vitreous, and occasionally with fibrinous exudates, posterior synechiae and macular edema. The uveitis was unilateral in two patients and bilateral in two. In three 10- to 14-year-old patients the uveitis resolved during corticosteroid treatment in 3 to 8 (mean 6) weeks. In a 4-year-old girl with positive antinuclear antibody titers bilateral uveitis lasted for 17 weeks. Two uveitis patients had recurrent episodes. Two patients had mucopurulent bilateral mild conjunctivitis which resolved in 3 to 5 days. All patients had symptoms of reactive arthritis and one had sacroiliitis. All tested patients were HLA-B27 positive. Our results indicate that in HLA-B27 positive children, especially after the age of 10 years, yersinia infection may occasionally trigger reactive iritis or conjunctivitis which often occur together with other HLA-B27 associated rheumatic diseases.
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References
Brewerton DA, Caffrey M, Nicholls A, Walters D & James DCO: Acute anterior uveitis and HL-A27. Lancet 2: 994–996, 1973
Kanski JJ: Anterior uveitis in juvenile rheumatoid arthritis. Arch Ophthalmol 95: 1794–1797, 1977
Kohl S, Jacobson JA, Nahmias A: Yersinia enterocolitica infections in children. J Pediatr 89: 77–79, 1976
Lang GK, Knapp W, Völcker HE: Yersinia-Uveitis. Klin Mbl Augenheilk 182: 156–158, 1983
Leino R, Mäkelä A-L, Tiilikainen A, Toivanen A: Yersinia arthritis in children. Scand J Rheumatol 9: 245–249, 1980
Mäki M, Vesikari I, Rantala I, Grönroos P: Yersiniosis in children. Arch Dis Childhood 55: 861–865, 1980
Oksala A: Ätiologie der Uveitis in Mittel-Finnland. Doc Ophthalmol 14: 399–411, 1960
Rodriquez WJ, Controni G, Cohen GJ, Florence B, Khan WN & Ross S. Yersinia enterocolitica enteritis in children. JAMA 242: 1978–1980, 1979
Saari KM, Laitinen O, Leirisalo M, Saari R. Ocular inflammation associated with yersinia infection. Am J Ophthalmol 89: 84–95, 1980
Saari M, Miettinen R, Alanko H. Uveitis: Report of a 10-year survey in Northern Finland. Can J Ophthalmol 10: 356–360, 1975
Saari M, Miettinen R, Tiilikainen A, Herva E, Lahti R. Acute anterior uveitis and HLA-B27 in families. Can J Ophthalmol 12: 4–11, 1977
Saari KM, Solja J, Häkli J, Seppänen S, Tiilikainen A, Koskimies S, Eriksson A, Frants R. Genetic background of acute anterior uveitis. Am J Ophthalmol 91: 711–720, 1981
Saari M, Vuorre I, Kaila J, Lahti R. Family studies of ocular manifestations in arthritis. Can J Ophthalmol 13: 144–151, (1978)
Schlaegel TF Jr, Weber JC. The sedimentation rate in endogenous uveitis. Arch Ophthalmol 73: 657–661, 1965
Smiley WK. The eye in juvenile rheumatoid arthritis. Trans Ophthalmol Soc UK 94: 817–829, 1974
Toivanen P, Toivanen A, Olkkonen L, Aantaa S. Hospital outbreak of Yersinia enterocolitica infection. Lancet 1: 801–803, 1973
Turunen O, Lundqvist C, Julin M, Holmlund G, Tiilikainen A, de la Chapelle A. Stimulatory and cytotoxic activity on human adult and fetal lymphocytes by heterologous antihuman fetal lymphocyte sera. Transplantation 27: 304–308, 1979
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Department of Ophthalmology, University of Tampere, PO Box 607, SF-33101 Tampere, Finland
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Saari, K.M., Mäki, M., Päivönsalo, T. et al. Acute anterior uveitis and conjunctivitis following yersinia infection in children. Int Ophthalmol 9, 237–241 (1986). https://doi.org/10.1007/BF00137536
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DOI: https://doi.org/10.1007/BF00137536