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Phase II study of L-alanosine (NSC 153353) in patients with advanced breast cancer

A Southwest Oncology Group study

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References

  1. Murthy YKS, Thiemann JE, Coronelli C et al.: Alanosine: A new antiviral and antitumor agent isolated from Streptomycis. Nature 211: 1198–1199, 1966

    Google Scholar 

  2. Creagan ET, Long HG, Ahmann DL et al.: Phase II evaluation of L-alanosine (NSC-153353) for patients with disseminated malignant melanoma. Am J Clin Oncol 7: 543–544, 1984

    Google Scholar 

  3. Rubin J, Hineman V, Moertel CG, et al.: A phase II study of alanosine in advanced large bowel carcinoma. Am J Clin Oncol 6: 191–193, 1983

    Google Scholar 

  4. Creagan ET, Schutt AJ, Ingle JN, et al.: Phase II clinical trial of 1-alanosine in advanced upper aerodigestive cancer. Cancer Treat Rep 67: 1047, 1983

    Google Scholar 

  5. Weick JK, Tranum BL, Morrison FS: The treatment of acute leukemia with continuous infusion L-alanosine. I.N.D. 1: 249–252.

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Authors and Affiliations

  1. University of Texas Health Science Center, San Antonio, Texas, USA

    Daniel D. Von Hoff & C. Kent Osborne

  2. Southwest Oncology Group Biostatistical Center, Seattle, Washington, USA

    Stephanie J. Green

  3. University of New Mexico, Albuquerque, New Mexico, USA

    James A. Neidhart

  4. University of Kansas Medical Center, Kansas City, Kansas, USA

    Carol Fabian

  5. Cleveland Clinic Foundation, Cleveland, Ohio, USA

    Thomas Budd

  6. Brooke Army Medical Center, Fort Sam Houston, USA

    James F. Boyd

Authors
  1. Daniel D. Von Hoff
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  2. Stephanie J. Green
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  3. James A. Neidhart
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  4. Carol Fabian
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  5. Thomas Budd
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  6. James F. Boyd
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  7. C. Kent Osborne
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Additional information

Address for offprints: Southwest Oncology Group (SWOG-8304), Operations Office, 5430 Fredericksburg Road, Suite #618, San Antonio, Texas 78229, USA

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Von Hoff, D.D., Green, S.J., Neidhart, J.A. et al. Phase II study of L-alanosine (NSC 153353) in patients with advanced breast cancer. Invest New Drugs 9, 87–88 (1991). https://doi.org/10.1007/BF00194553

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  • DOI: https://doi.org/10.1007/BF00194553

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