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Chromosome 7 short arm deletion and craniosynostosis a 7p-syndrome

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Summary

A patient with craniosynostosis and a small deletion of part of the short arm of chromosome 7 is described. A review of the literature indicates that craniosynostosis has occurred in at least four of the five infants (the fifth having microcephaly) affected by structural changes (resulting in deletion) within the terminal region of the short arm of chromosome 7.

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Authors and Affiliations

  1. Department of Medicine, University of Washington, School of Medicine, Children's Orthopedic Hospital and Medical Center, 4800 Sand Point Way NE, 98 105, Seattle, WA, USA

    Elspeth McPherson, Judith G. Hall & Robert Hickman

  2. Department of Pediatrics, University of Washington, School of Medicine, Children's Orthopedic Hospital and Medical Center, 4800 Sand Point Way NE, 98 105, Seattle, WA, USA

    Elspeth McPherson, Judith G. Hall & Robert Hickman

  3. Department of Pathology, University of Washington School of Medicine, Seattle, 98 195, Washington, WA, USA

    Bradley T. Gong, Thomas H. Norwood & Holger Hoehn

Authors
  1. Elspeth McPherson
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  2. Judith G. Hall
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  3. Robert Hickman
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  4. Bradley T. Gong
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  5. Thomas H. Norwood
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  6. Holger Hoehn
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Additional information

Supported by: National Foundation March of Dimes Grant CA-90, National Institutes of Health Grants, No. 5S01 RR05655-07 and No. P01 GM 15 253-08

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McPherson, E., Hall, J.G., Hickman, R. et al. Chromosome 7 short arm deletion and craniosynostosis a 7p-syndrome. Hum Genet 35, 117–123 (1976). https://doi.org/10.1007/BF00295627

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  • DOI: https://doi.org/10.1007/BF00295627

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