Skip to main content
Log in

Genetic mapping of the RET protooncogene on rat Chromosome 4

  • Short Communications
  • Published:
Mammalian Genome Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  • Blaugrund, J.E., Johns, M.M., Eby, Y.J., Ball, D.W., Hruban, R.H., Sidransky, D. (1994). RET proto-oncogene mutations in inherited and sporadic medullary thyroid cancer. Hum. Mol. Genet. 3, 1895–1897.

    Google Scholar 

  • Carlson, K.M., Dou, S., Chi, D., Scavarda, N., Toshima, K., Jackson, C.E., Wells, S.A., Goodfellow, P.J., Donis-Keller, H. (1994). Single missense mutation in the tyrosine kinase catalytic domain of the RET protooncogene is associated with multiple endocrine neoplasia type 2B. Proc. Natl. Acad. Sci. USA 91, 1579–1583.

    Google Scholar 

  • Cass, D.T., Zhang, A.L., Morthope, J. (1992). Aganglionosis in rodents. J. Pediatr. Surg. 27, 351–356.

    Google Scholar 

  • Ceccherini, I., Bocciardi, R., Yin, L., Pasini, B., Hofstra, R., Takahashi, M., Romeo, G. (1993). Exon structure and flanking intronic sequences of the human RET proto-oncogene. Biochem. Biophys. Res. Commun. 196, 1288–1295.

    Google Scholar 

  • Copeland, N.G., Jenkins, N.A., Gilbert, D.J., Eppig, J.T., Maltais, L.J., Miller, J.C., Dietrich, W.F., Weaver, A., Lincoln, S.E., Steen, R.G., Stein, L.D., Nadeau, J.H., Lander, E.S. (1993). A genetic linkage map of the mouse: current applications and future prospects. Science 262, 57–66.

    Google Scholar 

  • Donis-Keller, H., Dou, S., Chi, D., Carlson, K.M., Toshima, K., Lairmore, T.C., Howe, J.R., Moley, J.F., Goodfellow, P.J., Wells, S.A. (1993). Mutations in the RET proto-oncogene are associated with MEN 2A and FMTC. Hum. Mol. Genet. 2, 851–856.

    Google Scholar 

  • Edery, P., Lyonnet, S., Mulligan, L.M., Pelet, A., Dow, E., Abel, L., Holder, S., Nihoul-Fekete, C., Ponder, B.A.J., Munnich, A. (1994). Mutations of the RET proto-oncogene in Hirschsprung's disease. Nature 367, 378–380.

    Google Scholar 

  • Eng, C., Smith, D.P., Mulligan, L.M., Nagai, M.A., Healey, C.S., Ponder, M.A., Gardner, E., Scheumann, G.F.W., Jackson, C.E., Tunnaclife, A., Ponder, B.A.J. (1994). Point mutation with the tyrosine kinase domain of the RET proto-oncogene in multiple endocrine neoplasia type 2B and related sporadic tumours. Hum. Mol. Genet. 3, 237–241.

    Google Scholar 

  • Hofstra, R.M.W., Landsvater, R.M., Ceccherini, I., Stulp, R.P., Stelwagen, T., Yin, L., Pasini, B., Hoppener, J.W.M., van Amstel, H.K.P., Romeo, G., Lips, C.J.M., Buys, C.H.C.M. (1994). A mutation in the RET protooncogene associated with multiple endocrine neoplasia type 2B and sporadic medullary thyroid carcinoma. Nature 367, 375–376.

    Google Scholar 

  • Ishizaka, Y., Itoh, F., Tahira, T., Ikeda, I., Sugimura, T., Tucker, J., Fertitta, A., Carrano, A.V., Nagao, M. (1989). Human RET proto-oncogene mapped to chromosome 10q11.2. Oncogene 4, 1519–1521.

    Google Scholar 

  • Iwamoto, T., Taniguchi, M., Asai, N., Ohkusu, K., Nakashima, I., Takahashi, M. (1993). cDNA cloning of mouse RET proto-oncogene and its sequence similarity to the cadherin superfamily. Oncogene 8, 1087–1091.

    Google Scholar 

  • Lincoln, S.E., Daly, M., Lander, E.S. (1992). Constructing Genetic Maps with MAPMAKER/EXP 3.0. Whitehead Institute Technical Report, 3rd ed.

  • Mulligan, L.M., Kwok, J.B.J., Healey, C.S., Eldson, M.J., Eng, C., Gardner, E., Love, D.R., Mole, S.E., Moore, J.K., Papi, L., Ponder, M.A., Telenius, H., Tunnaclife, A., Ponder, B.A.J. (1993). Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A. Nature 363, 458–460.

    Google Scholar 

  • Mulligan, L.M., Eng, C., Healey, C.S., Clayton, D., Kwok, J.B.J., Gardner, E., Ponder, M.A., Frilling, A., Jackson, C.E., Lehnert, H., Neumann, H.P.H., Thibodeau, S.N., Ponder, B.A.J. (1994). Specific mutations of the RET proto-oncogene are related to disease phenotype in MEN 2A and FMTC. Nature Genet. 6, 70–74.

    Google Scholar 

  • Romeo, G., Ronchetto, P., Yin, L., Barone, V., Seri, M., Ceccherini, I., Pasini, B., Bocciardi, R., Lerone, M., Kaariainen, H., Martucciello, G. (1994). Point mutations affecting the tyrosine kinase domain of the RET proto-oncogene in Hirschsprung's disease. Nature 367, 377–378.

    Google Scholar 

  • Schuchardt, A., D'Agati, V., Larsson-Blomberg, L., Costantini, F., Pachnis, V. (1994). Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor RET. Nature 367, 380–383.

    Google Scholar 

  • Takahashi, M., Buma, Y., Hiai, H. (1989). Isolation of the RET protooncogene cDNA with an amino-terminal signal sequence. Oncogene 4, 805–806.

    Google Scholar 

  • Van Heyningen, V. (1994). One gene—four syndromes. Nature 367, 319–320.

    Google Scholar 

  • Yamada, J., Kuramoto, T., Serikawa, T. (1994). A rat genetic linkage map and comparative maps for mouse or human homologous rat genes. Mamm. Genome 5, 63–83.

    Google Scholar 

  • Zedenius, J., Wallin, G., Hamberger, B. Nordenskjold, M., Weber, G., Larsson, C. (1994). Somatic and MEN 2A de novo mutations identified in the RET proto-oncogene by screening of sporadic MTC:s. Hum. Mol. Genet. 3, 1259–1262.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Canzian, E., Ushijima, T., Nagao, M. et al. Genetic mapping of the RET protooncogene on rat Chromosome 4. Mammalian Genome 6, 433–435 (1995). https://doi.org/10.1007/BF00355647

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00355647

Keywords

Navigation