Abstract
The effects of δ 9-THC, LSD-25 and scopolamine on continuous, spontaneous alternation of the hooded rat in the Y-maze were determined. LSD and scopolamine decreased the number of arm entries (responsivity) while concomitantly reducing percent alternation. THC however, reduced responsivity and percent alternation more at the lower dose (1 mg/kg) when compared to control than at the higher dose (3 mg/kg). Only scopolamine induced a significant increase in stimulus perseveration. The results are discussed in relation to the advantages afforded by the continuous spontaneous alternation procedure.
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Drew, W.G., Miller, L.L. & Baugh, E.L. Effects of δ9-THC, LSD-25 and scopolamine on continuous, spontaneous alternation in the Y-maze. Psychopharmacologia 32, 171–182 (1973). https://doi.org/10.1007/BF00428688
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DOI: https://doi.org/10.1007/BF00428688