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Primary eosinophilic granuloma of the frontal lobe

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Summary

The clinical symptoms, pathological findings and surgical treatment of a case of primary frontal lobe eosinophilic granuloma are presented. Initially a frontal mass was detected that clinically seemed like a low-growth tumor. After operation, the histological, cytochemical and ultrastructural studies showed positive acid phosphatase, α-naftil-esterase, oil-red and PAS reactions of tumoral cells and the presence of rod-shaped bodies in proliferative histiocytes, all which confirmed the pathological diagnosis of eosinophilic granuloma. Other osseous or visceral histiocytosis-X signs were not observed. The patient remains asymptomatic after a postoperative follow-up of 2 years.

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References

  • Beatty, E.C.: Eosinophilic granuloma of the parotid gland and thymus. Am. J. Dis. Child. 105, 507 (1963)

    Google Scholar 

  • Benisch, B., Peison, B., Carter, H.: Histiocytosis X of the skin in an elderly man. Am. J. Clin. Pathol. 67, 36–40 (1977)

    Google Scholar 

  • Braunstein, G.D., Whitaker, J.N., Kohler, P.O.: Cerebral dysfunction in Hand-Schuller-Christian disease. Arch. Intern. Med. 132, 387–390 (1973)

    Google Scholar 

  • Cardozo, L.J., Bailey, I.C., Billinghurst, J.R.: Non osseous eosinophilic granuloma presenting as acute trasverse myelitis. Br. J. Surg. 61, 747–749 (1974)

    Google Scholar 

  • Davidson, A.R.: Eosinophilic granuloma of the lung. Br. J. Dis. Chest. 70, 125–128 (1976)

    Google Scholar 

  • Hou-Jensen, K., Rawlinson, D.G., Hendrickson, M.: Proliferating histiocytic lesion. Cancer 32, 809–821 (1973)

    Google Scholar 

  • Kauffman, A., Bukberg, P.R., Werlin, S.: Multifocal eosinophilic granuloma (Hand-Schuller-Christian disease). Am. J. Med. 60, 541–548 (1976)

    Google Scholar 

  • Kepes, J.J., Kepes, M.: Predominantly cerebral forms of histiocytosis X. Acta Neuropathol. 14, 77–98 (1969)

    Google Scholar 

  • Nezelof, C., Basset, F., Rousseau, M.F.: Histiogenetic arguments for a Langerhans cell origin. Biol. Med. 18, 365–371 (1973)

    Google Scholar 

  • Rube, J., de la Pava, S., Pickren, J.W.: Histiocytosis X with involvement of the brain. Cancer 20, 486–492 (1967)

    Google Scholar 

  • Shamoto, M.: Mitotic histiocytes and intranuclear Langerhans cell granules in histiocytosis X. Virchows Arch. B Cell. Path. 24, 87–90 (1977)

    Google Scholar 

  • Sivalingam, S., Corkill, G., Ellis, W.G., Claiche, J.R.: Focal eosinophilic granuloma of the temporal lobe. J. Neurosurg. 47, 941–945 (1977)

    Google Scholar 

  • Vazquez, J.J., Ayestaran, J.R.: Eosinophilic granuloma of the stomach similar to that of bone. Virchows Arch. A Path. Anat. and Histol., 366, 107–111 (1975)

    Google Scholar 

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Cerdá-Nicolas, M., Broseta, J., Peydrò-Olaya, A. et al. Primary eosinophilic granuloma of the frontal lobe. Virchows Arch. A Path. Anat. and Histol. 388, 221–228 (1980). https://doi.org/10.1007/BF00430690

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