Abstract
An apparently balanced de novo constitutional translocation (7;13) (q36;q13) was detected on peripheral lymphocytes and fibroblasts of a 14-month-old boy. The patient presented a facial dysmorphism with hydrocephaly and mental retardation associated with a Wilms' tumor. A pure coincidence of random association cannot be ruled out but one can equally assert the plausibility of a minimal unnoticed deletion or a position effect.
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Bernard, J.L., Baeteman, M.A., Mattei, J.F. et al. Wilms' tumor, malformative syndrome, mental retardation and de novo constitutional translocation, t(7;13)(q36;q13). Eur J Pediatr 141, 175–177 (1984). https://doi.org/10.1007/BF00443220
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DOI: https://doi.org/10.1007/BF00443220