Summary
After kanamycin induced degeneration of outer hair cells from guinea pigs the tuning properties of primary auditory nerve fibres are compared with those of normal untreated guinea pigs. The existence of fibres with no alteration of the tuning properties leads to the conclusion that there is no neural interaction between inner and outer hair cells needed to enhance the frequency selectivity.
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This study was supported by the Deutsche Forschungsgemeinschaft (Bo 421/1-3). Kanamycin was kindly provided by Chemie Grünenthal.
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Romahn, G., Boerger, G. Filter function of the guinea pig cochlea after degeneration of outer hair cells. Arch Otorhinolaryngol 215, 223–229 (1977). https://doi.org/10.1007/BF00463060
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DOI: https://doi.org/10.1007/BF00463060