Summary
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1.
Mutations at thestoned locus ofDrosophila melanogaster produce a reversible temperature-sensitive debilitation. At permissive temperatures they also exhibit an unusual jump response to a light-off stimulus.
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2.
An increase in the amplitude of the off-transient of the electroretinogram (ERG) is associated with this abnormal jump. Both the jump response and the increased amplitude of the off-transient are shown to be dependent on the duration of the light pulse prior to the light-off stimulus.
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3.
Instoned flies which are light adapted, the jump response, as measured by recording from the indirect flight muscles, is seen to habituate with increasing light-off frequency. This habituation corresponds to the decrease in the amplitude of the off-transient that also occurs with high-frequency stimulation.
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Another visual mutanttan, removes the off and on-transients of the ERG.
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The combining of thestoned mutation withtan in thetan, stoned double mutant results in the loss of the jump behavior as well as the partial restoration of the off-transient to an otherwisetan-like ERG. The relationship between the increase in the amplitude of the off-transient instoned flies and the eliciting of the jump response is discussed.
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Kelly, L.E. An altered electroretinogram transient associated with an unusual jump response in a mutant ofDrosophila . Cell Mol Neurobiol 3, 143–149 (1983). https://doi.org/10.1007/BF00735278
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DOI: https://doi.org/10.1007/BF00735278