Summary
Six patients are described who developed a wide variety of neurological manifestations heralding systemic lupus erythematosus (SLE), which included epileptic seizures, stroke, peripheral polyradiculoneuro pathy similar to Guillain-Barré syndrome, transverse my elopathy and multifocal disorders with remitting course mimicking multiple sclerosis. The peculiarity of these cases was that the neurological disorders remained the only manifestations of SLE for many years and the nervous system appeared to be the main target even after the development of systemic SLE. In five patients the prognosis was favourable and corticosteroid treatment led to prolonged remission.
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Tola, M.R., Granieri, E., Caniatti, L. et al. Systemic lupus erythematosus presenting with neurological disorders. J Neurol 239, 61–64 (1992). https://doi.org/10.1007/BF00862972
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DOI: https://doi.org/10.1007/BF00862972