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A geometric framework for polymer folding

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Abstract

The problem of finding the folding pathway of a polymer, a fundamental issue in the field of molecular biophysics, is viewed from a geometrical standpoint. A riemannian metric on conformation space related to hydrodynamical features of the system and a drift related to the potential are used to derive a diffusion equation governing the time dependent probability in conformation space. The thermodynamic equilibrium limit is found to be consistent with Boltzmann's measure.

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Authors and Affiliations

  1. Departamento de Matemática of the Universidad Nacional del Sur and Instituto de Matemática (INMABB-CQNICET), Av. Alem 1253, 8000, Bahia Blanca, Argentina

    Hernán Cendra & Ariel Fernández

  2. Departamento de Fisica, Universidad Nacional del Sur, Av. Alem 1253, 8000, Bahia Blanca, Argentina

    Walter Reartes

Authors
  1. Hernán Cendra
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  2. Ariel Fernández
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  3. Walter Reartes
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Cendra, H., Fernández, A. & Reartes, W. A geometric framework for polymer folding. J Math Chem 19, 331–336 (1996). https://doi.org/10.1007/BF01166723

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  • DOI: https://doi.org/10.1007/BF01166723

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