Abstract
From October 1987 to March 1991, 21 (8%) superficial early cancers were found among 256 early colorectal cancers (Dukes A and B1). Superficial early cancers were defined as early cancers less than 3 mm in height. These tumors were found scattered throughout the large intestine and were often observed as reddish spots, which were easily overlooked without careful observation. Histologically, 19 (90%) of them were well-differentiated adenocarcinomas, and five (24%) of them reached the submucosal layer. Eighteen (86%) of them were not associated with adenoma.
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Iishi, H., Kitamura, S., Nakaizumi, A. et al. Clinicopathological features and endoscopic diagnosis of superficial early adenocarcinomas of the large intestine. Digest Dis Sci 38, 1333–1337 (1993). https://doi.org/10.1007/BF01296086
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DOI: https://doi.org/10.1007/BF01296086