Skip to main content
SpringerLink
Log in

Papillary thyroid carcinoma in Danish patients with familial adenomatous polyposis

  • Original Articles
  • Published:
International Journal of Colorectal Disease Aims and scope Submit manuscript

Abstract

All patients from the nationwide Danish Polyposis Register have been followed up with regard to thyroid carcinoma. During the period 1943–1985, 2/107 Danish women and 0/138 men developed papillary thyroid carcinoma after the diagnosis of familial adenomatous polyposis. The expected number among females was 0.02 resulting in an observed/expected ratio of 100 (95% confidence limits 12–361). Consequently, thyroid carcinoma should be included among the extracolonic lesions, which may develop in any female polyposis patient. However, regular thyroid examination is not indicated, as thyroid carcinoma is uncommon and as the prognosis is excellent.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Crail HW (1949) Multiple primary malignancies arising in the rectum, brain and thyroid. US Nav Med Bull 49:123–128

    Google Scholar 

  2. Thompson JS, Harned RK, Anderson JC, Hodgson PE (1983) Papillary carcinoma of the thyroid and familial polyposis coli. Dis Colon Rectum 26:583–585

    Google Scholar 

  3. Plail RO, Bussey HJR, Glazer G, Thomson JPS (1987) Adenomatous polyposis: an association with carcinoma of the thyroid. Br J Surg 74:377–380

    Google Scholar 

  4. Camiel MR, Mule JE, Alexander LL, Benninghoff DL (1968) Association of thyroid carcinoma with Gardner's syndrome in siblings. N Engl J Med 278:1056–1058

    Google Scholar 

  5. Alm T, Licznerski G (1973) The intestinal polyposes. Clin Gastroenterol 2:577–602

    Google Scholar 

  6. Bülow S, Holm NV, Hauge M (1986) The incidence and prevalence of familial polyposis coli. Scand J Soc Med 14:67–74

    Google Scholar 

  7. Clemmesen J (1977) Statistical studies in the aetiology of malignant neoplasms. V. Trends and risks, Denmark 1943–1977. Acta Pathol Microbiol Scand [Suppl 261]

  8. The Danish Cancer Registry 1985. Cancer incidence in Denmark 1981 and 1982. The Danish Cancer Society, Copenhagen

    Google Scholar 

  9. Monson RR (1974) Analysis of relative survival and proportional mortality. Comp Biomed Res 7:325–332

    Google Scholar 

  10. Nomura S, Miyakawa M, Makiuchi M, Furihata R (1976) Follow up study for well differentiated carcinoma of the thyroid. Thyroid research. Excerpta Medica, Amsterdam, pp 579–582

    Google Scholar 

  11. Wang C (1978) Thyroid cancer. In: Werner SC, Ingbar SH (ed) The thyroid. A fundamental and clinical text. Harper & Row, New York, p 567

    Google Scholar 

  12. Phade VR, Lawrence WRR, Max MH (1981) Familial papillary carcinoma of the thyroid. Arch Surg 116:836–837

    Google Scholar 

  13. Robinson Baker R, Hyland J (1985) Papillary carcinoma of the thyroid gland. SGO 161:546–550

    Google Scholar 

  14. Bülow S (1986) Clinical features in familial polyposis coli. Results of the Danish polyposis register. Dis Colon Rectum 29:102–107

    Google Scholar 

  15. Bülow S, Lauritsen KB, Johansen Aa, Svendsen LB, Søndergaard JO (1985) Gastroduodenal polyps in familial polyposis coli. Dis Colon Rectum 28:90–93

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. The Danish Polyposis Register, Department of Surgical Gastroenterology, Bispebjerg Hospital, Copenhagen

    S. Bülow

  2. The Institute of Medical Genetics, Odense

    N. V. Holm

  3. Department of Oncology and Radiotherapy, Odense Hospital, Odense

    N. V. Holm

  4. The Danish Cancer Registry, Copenhagen, Denmark

    A. Mellemgaard

  5. Department of Surgical Gastroenterology, Hvidovre Hospital, DK-2650, Hvidovre, Denmark

    S. Bülow

Authors
  1. S. Bülow
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. N. V. Holm
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. A. Mellemgaard
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bülow, S., Holm, N.V. & Mellemgaard, A. Papillary thyroid carcinoma in Danish patients with familial adenomatous polyposis. Int J Colorect Dis 3, 29–31 (1988). https://doi.org/10.1007/BF01649679

Download citation

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01649679

Keywords

Search

Navigation