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Hemoglobin variation in macaques

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Abstract

A total of 1,333 hemolysates obtained from six different species of macaques,M. fuscata, M. cyclopis, M. mulatta, M. speciosa, M. nemestrina, andM. irus, were examined by starch gel electrophoresis. Three major hemoglobins, tentatively designated S, F, and P, and one minor component were found among the samples, in which P and a minor component were observed only in some samples ofM. irus. The hemoglobin types observed and their incidence in each species agreed, on the whole, with results reported by earlier workers. However, in addition to marked differences among macaque species, there existed striking geographical differences in the distribution of hemoglobin components within the same species. The distribution of hemoglobin types observed among the species are presented, together with the results of the determination of hemoglobin concentration in a two-band type and those of the alkali-resistant pigment of the macaques.

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References

  • Barnicot, N. A. &C. J. Jolly, 1966. Haemoglobin polymorphism in the Orang Utan and an animal with four major haemoglobins.Nature, London, 210: 640–642.

    Google Scholar 

  • --, --,E. R. Huehns, & N. Dance, 1965. Red cell and serum protein variations in baboons. In:The Baboon in Medical Reseach, Vol. 1,H. Vagtborg (ed.), Univ. Texas Press, pp. 323–338.

  • , 1966. Biochemical studies on haemoglobin variants of the irus macaque.Proc. Roy. Soc. London, Ser. B, 165: 224–244.

    Google Scholar 

  • Bonaventura, J. &A. Riggs, 1967. Polymerization of hemoglobins of mouse and man: structural basis.Science, 158: 800–802.

    PubMed  Google Scholar 

  • Buettner-Janusch, J., 1963. Hemoglobins and transferrins of baboons.Folia primat., 1: 73–87.

    Google Scholar 

  • , 1961. Alkali-resistant haemoglobins in Prosimian primates.Nature, London, 192: 669.

    Google Scholar 

  • , 1961. Multiple haemoglobins and transferrins in a macaque sibship.Nature, London, 192: 948–950.

    Google Scholar 

  • -- &V. Buettner-Janusch, 1964. Hemoglobins of primates. In:Evolutionary and Genetic Biology of Primates, Vol. 2,J. Buettner-Janusch (ed.), Academic Press, pp. 75–90.

  • Crawford, M. H., 1966. Hemoglobin polymorphism inMacaca nemestrina.Science, 154: 398–399.

    PubMed  Google Scholar 

  • Gottlieb, L. I. &J. L. van Lancker, 1963. Electrophoretic patterns ofMacaca mulatta andMacaca nemestrina hybrid haemoglobin.Nature, London, 200: 900–901.

    Google Scholar 

  • Hoffman, H. A., A. J. Gottlieb, &W. G. Wisecup, 1967. Hemoglobin polymorphism in chimpanzees and gibbons.Science, 156: 944.

    PubMed  Google Scholar 

  • Ishimoto, G., T. Toyomasu, &K. Uemura, 1968. Intraspecies variations of red cell enzymes and hemoglobin inMacaca irus.Primates, 9: 395–408.

    Google Scholar 

  • Jacob, G. F. &N. C. Tappen, 1957. Abnormal haemoglobins in monkeys.Nature, London, 180: 241–242.

    Google Scholar 

  • , 1958. Haemoglobin in monkeys.Nature, London, 181: 197–198.

    Google Scholar 

  • Jolly, C. J. &N. A. Barnicot, 1966. Serum and red cell protein variations of the Celebes black ape.Folia primat., 4: 206–220.

    Google Scholar 

  • Kitchen, H., J. W. Eaton, &V. G. Stenger, 1968. Hemoglobin types of adult, fetal, and newborn subhuman primates:Macaca speciosa.Arch. Biochem. Biophys., 123: 227–234.

    PubMed  Google Scholar 

  • Kitchin, F. D., N. A. Barnicot, & C. J. Jolly, 1965. Variations in the group specific (Gc) component and other blood proteins of baboons. In:The Baboon in Medical Research, Vol. 2,H. Vagtborg (ed.), Univ. Texas Press, pp. 637–657.

  • Lehmann, H. &R. Huntsman, 1966.Man's Haemoglobins. Amsterdam, North-Holland.

    Google Scholar 

  • Matsuda, G., T. Maita, H. Takei, H. Ota, M. Yamaguchi, T. Miyauchi, &M. Migita, 1968. The primary structure of adult hemoglobin fromMacaca mulatta monkey.J. Biochem., Tokyo, 64: 279–282.

    Google Scholar 

  • Omoto, K., S. Harada, T. Tanaka, H. Nigi, &W. Prychodko, 1970. Distribution of the electrophoretic variants of serum alpha1-antitrypsin in six species of the macaques.Primates, 11: 215–228.

    Google Scholar 

  • Poulik, M. D., 1957. Starch gel electrophoresis in discontinuous system of buffers.Nature, London, 180: 1477–1479.

    Google Scholar 

  • Tuttle, A. H., F. E. Newsome, C. H. Jackson, &R. R. Overman, 1961. Hemoglobin types ofMacaca irus andMacaca mulatta monkeys.Science, 133: 578–579.

    PubMed  Google Scholar 

  • Winterhalter, K. H. &E. R. Huehns, 1964. Preparation, properties, and specific recombination ofαβ-globin subunits.J. biol. Chem., 239: 3699–3705.

    PubMed  Google Scholar 

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Ishimoto, G., Tanaka, T., Nigi, H. et al. Hemoglobin variation in macaques. Primates 11, 229–241 (1970). https://doi.org/10.1007/BF01793889

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  • DOI: https://doi.org/10.1007/BF01793889

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