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Direct fluorination of carcinogenic polycyclic aromatic hydrocarbons. 6-Fluorobenzo[a]pyrene

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Summary

Xenon difluoride reacts with benzo[a]pyrene (BaP) in dichloromethane solution in an open system to give 6-fluorobenzo[a]pyrene. This method constitutes a direct route to fluorine substituted carcinogenic polycyclic aromatic hydrocarbons.

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Authors and Affiliations

  1. Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem, (Israel)

    I. Agranat, M. Rabinovitz, H. Selig & C. -H. Lin

Authors
  1. I. Agranat
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  2. M. Rabinovitz
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  3. H. Selig
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  4. C. -H. Lin
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Additional information

Acknowledgment. This work was financed in part by a grant from The Israel Commission for Basic Research.

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Agranat, I., Rabinovitz, M., Selig, H. et al. Direct fluorination of carcinogenic polycyclic aromatic hydrocarbons. 6-Fluorobenzo[a]pyrene. Experientia 32, 417–418 (1976). https://doi.org/10.1007/BF01920768

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