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Marchiafava-Bignami disease. A case studied by structural and functional brain imaging

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Summary

Marchiafava-Bignami disease (MBD) is a rare complication of chronic alcoholism. The clinical features, X-ray, CT and MRI findings are well documented. However, functional brain imaging has not been used in cases of MBD. We used single-photon emission computed tomography (SPECT) to monitor the regional cerebral blood flow in a patient suffering from a acute form of MBD, from which he subsequently recovered. Several abnormalities were found. A more frequent use of functional brain imaging in MBD could improve our knowledge of pathogenesis and prognosis for MBD.

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Authors and Affiliations

  1. Service de Psychiatrie B1, Hôpital Gaston Doumergue, C.H.U., 30000, Nimes, France

    T. Humbert & P. Chabrand

  2. Département d'Imagerie Médicale, Hôpital Gaston Doumergue, C.H.U., 30000, Nimes, France

    P. De Guilhermier & F. M. Lopez

  3. Service Central de Médecine Nucléaire et de Biophysique Médicale, Hôpital Gaston Doumergue, C.H.U., 30000, Nimes, France

    C. Maktouf & G. Grasset

Authors
  1. T. Humbert
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  2. P. De Guilhermier
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  3. C. Maktouf
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  4. G. Grasset
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  5. F. M. Lopez
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  6. P. Chabrand
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Humbert, T., De Guilhermier, P., Maktouf, C. et al. Marchiafava-Bignami disease. A case studied by structural and functional brain imaging. Eur Arch Psychiatry Clin Nuerosci 242, 69–71 (1992). https://doi.org/10.1007/BF02191548

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  • DOI: https://doi.org/10.1007/BF02191548

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