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Nebulized salbutamol vs salbutamol and ipratropium combination in asthma

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Abstract

Objective : To see the additional benefit of combined frequent nebulization with salbutamol and ipratropium bromide in acute attack of asthma with moderate severity.Methods : Fifty asthmatic children in the age range of 6–14 years were divided into two equal groups. Group I children were nebulized with three doses of Salbutamol alone (0.03 ml/kg/dose) and Group II children were given combined nebulization of Salbutamol (dose as in group I) and Ipratropium bromide (250 Μgm/dose for three doses) at 20 minutes interval. Children were observed at 15, 30, 60,120,180 and 240 minutes interval.Results : A significant improvement in % of PEFR starting at 30 minutes and lasting the entire study period of 4 hours was noted in both the groups. However on analysis of varience the results were better in group II.Conclusion : Frequent combined nebulization with Salbutamol and Ipratropium bromide is beneficial in acute asthma of moderate severity.

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  1. Department of Pediatrics, Pt. B.D.Sharma Postgraduate Institute of Medical Sciences, Rohtak, Haryana, India

    Anita Sharma & Arvind Madaan

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  1. Anita Sharma
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  2. Arvind Madaan
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Correspondence to Anita Sharma.

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Sharma, A., Madaan, A. Nebulized salbutamol vs salbutamol and ipratropium combination in asthma. Indian J Pediatr 71, 121–124 (2004). https://doi.org/10.1007/BF02723090

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