Summary
Sixty consecutive patients who underwent Charnley low friction arthroplasty of the hip were investigated for the presence of deep vein thrombosis. All were given Dextran 70 prophylaxis. Using bilateral venography on the ninth post-operative day an incidence of 6.6 per cent was found. The findings are discussed.
Similar content being viewed by others
References
Ahlberg, A., Nylander, G., Robertson, B., Cronberg, S. and Nilsson, I. M. 1968. Dextran in prophylaxis of thrombosis in fractures of the hip. Acta Chir. Scand. Suppl. No. 387, 83.
Arfors, K. E., Hint, H. C., Dhall, D. P. and Matheson, N. A. 1968. Counteraction of platelet activity at sites of laser-induced endothelial trauma. Brit. Med. J., iv, 430
Atkins, P. and Hawkins, I. A. 1965. Detection of venous thrombosis in the legs. Lancet, ii, 1217.
Bennett, P., Dhall, D. P., McKenzie, F. N. and Matheson, N. A. 1966. Effects of dextran infusion on the adhesiveness of human blood-platelets. Lancet, ii, 1001.
Bonnar, J. and Walsh, J. 1972. Prevention of thrombosis after pelvic surgery by British Dextran 70. Lancet i, 614.
Borgstrom, S., Gelin, L. E. and Zederfeldt, B. 1959. The formation of vein thrombi following tissue injury. Acta Chir. Scand. Suppl. No. 247, pp. 1–36.
Bygdeman, S. and Eliasson, R. 1967. Effects of dextrans on platelet adhesiveness and aggregation. Scand. J. Chir. Lab. Invest. 20, 17.
Carter, A. E. and Eban, R. 1973. The prevention of post-operative deep venous thrombosis with Dextran 70. Brit. J. Surg. 60, 681.
Charnley, J. 1970. The long-term results of low fraction arthroplasty of the hip. Internal Publication No. 25. Centre for Hip Surgery, Wrightington Hospital. pp. 1–14.
Coventry, M. B., Beckenbaugh, R. D., Nolan, D. R. and Ilstrup, D. M. 1974. 2,012 total hip arthroplasties: a study of postoperative course and early complications. J. Bone Joint Surg. 56A, 273.
Dhall, D. P., Bennett, P. and Matheson, N. A. 1968. Effects of dextran on platelet behaviour after abdominal operations. Acta Chir. Scand. Suppl. No. 387, 75.
Evans, D. S. and Cockett, F. B. 1969. Diagnosis of deep vein thrombosis with an ultrasonic doppler technique. Brit. Med. J. ii, 802.
Evarts, C. M. and Feil, E. J. 1971. Prevention of thromboembolic disease after elective surgery of the hip. J. Bone Joint Surg. 53A, 1271.
Flanc, D., Kakkar, V. V. and Clarke, M. B. 1968. The detection of venous thrombosis of the legs using 125 labelled fibrinogen. Brit. J. Surg. 55, 742.
Hamilton, H. W., Crawford, J. S., Cardiner, J. H. and Wiley, A. M. 1970. Venous thrombosis in patients with fracture of the upper end of the femur. J. Bone Joint Surg. 52B, 268.
Harris, J., Lightowler, C. D. R. and Todd, R. C. 1972. Total hip replacement in inflammatory hip disease using the Charnley prosthesis. Brit. Med. J. ii, 750.
Harris, W. H., Salzman, E. W. and De Sanctis, R. W. 1967. The prevention of thromboembolic disease by prophylactic anticoagulation. J. Bone Joint Surg. 49A, 81.
Hobbs, J. T. and Davies, J. W. L. 1960. Detection of venous thrombosis with136l labelled fibrinogen in the rabbit. Lancet ii, 134.
Hunter, W. C., Drygier, J. J., Kennedy, J. C.et al. 1945. Etiology and prevention of thrombosis of the deep leg veins: a study of 400 cases. Surgery 17, 178.
Huttunen, H. J., Mattila, M. A. K., Hakalehto, J., Kettumen, K., Rehnberg, V. and Babinski, M. 1971. Single infusion of Dextran 70 in the prophylaxis of post-oprative deep venous thrombosis. Anna Chir. et Gynae Fenniae 60, 119.
Johnsson, S. R., Bygdeman, S. and Eliasson, R. 1968. Effect of dextran on postoperative thrombosis. Acta Chir. Scand. Suppl. No. 387, 80.
Kakkar, V. V., Flanc, C., Howe, C. T., O’Shea, M. J. and Flute, P. T. 1969. Treatment of deep vein thrombosis. A trial of heparin streptokinase and arvin. Brit. Med. J. i, 806.
Kakkar, V. V., Howe, C. T., Nicolaides, A. N., Renney, J. T. G. and Clarke, M. B. 1970. Deep vein thrombosis of the leg—is there a “high risk” group. Am. J. Surg. 120, 527.
Kakkar, V. V., Corrigan, T. P., Fossard, D. P. 1973. Prevention of fatal pulmonary embolism using low doses of subcutaneous heparin. Eur. Surg. Res. 5: Suppl. 2, 25.
Lambie, J. M., Barber, D. C., Dhall, D. P. and Matheson, N. A. 1970. Dextran 70 in prophylaxis of postoperative venous thrombosis. A controlled trial. Brit. Med. J. ii, 144.
Le Quesne, L. P. 1974. Relation between deep vein throbbosis and pulmonary embolism in surgical patients. New Eng. J. Med. 24, 1292.
McManus, F. 1975. Low friction arthroplasty of, the hip: an analysis of 597 cases. J. Irish Med. Assoc. 68, 317.
Negus, D. 1967. Warning of massive pulmonary embolism. Brit. Med. J. iii, 559.
Negus, D. 1974. The diagnosis and management of venous thrombosis. Teach-In 3, 9.
Nicolaides, A. N., Kakkar, V. V., Field, E. S. and Renney, J. J. G. 1971. The origin of deep vein thrombosis: a venographic study. Brit. J. Radiology 44, 653.
Ring, P. A. 1974. Total replacement of hip joint. J. Bone Joint Surg. 56B, 44.
Sheehan, J. M. 1974. Review of total hip replacement—Charnley type. J. Irish Med. Assoc. 67, 363.
Todd, R. C., Lightowler, C. D. R. and Harris, J. 1972. Total hip replacement in osteoarthrosis using the Charnely prosthesis. Brit. Med. J. ii, 752.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
McManus, F. The incidence of deep venous thrombosis after total hip replacement using Dextran 70 prophylaxis—A venographic study. IJMS 145, 201–206 (1976). https://doi.org/10.1007/BF02938945
Issue Date:
DOI: https://doi.org/10.1007/BF02938945