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Malignization of a vestibular schwannoma 13 years after radiation therapy

Malignisierung eines Vestibularisschwannoms 13 Jahre nach Bestrahlung

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Abstract

This article presents a case of malignant transformation of vestibular schwannoma 13 years after stereotactic radiation therapy, which lead to an acute life-threatening condition. Although the observation is currently only based on case reports, an increasing number of these support the hypothesis that there is a relevant risk of malignant transformation in the long-term course of previously irradiated vestibular schwannomas. Therefore, long-term MRI follow-up should be considered.

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Authors and Affiliations

  1. Klinik für Neurochirurgie, University Hospital Halle, Ernst-Grube-Straße 40, 06120, Halle, Germany

    S. Simmermacher & C. Strauss

  2. Klinik für Strahlentherapie, University Hospital Halle, Halle, Germany

    D. Vordermark

  3. Klinik für Hämatologie und Onkologie, University Hospital Halle, Halle, Germany

    T. Kegel

Authors
  1. S. Simmermacher
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  2. D. Vordermark
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  3. T. Kegel
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  4. C. Strauss
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Correspondence to S. Simmermacher.

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Conflict of interest

S. Simmermacher, D. Vordermark, T. Kegel, and C. Strauss declare that they have no competing interests.

This article does not contain any studies with human participants or animals performed by any of the authors. Consent was obtained from all patients identifiable from images or other information within the manuscript. In the case of underage patients, consent was obtained from a parent or legal guardian.

The supplement containing this article is not sponsored by industry.

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Simmermacher, S., Vordermark, D., Kegel, T. et al. Malignization of a vestibular schwannoma 13 years after radiation therapy. HNO 65 (Suppl 2), 153–157 (2017). https://doi.org/10.1007/s00106-017-0362-8

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  • DOI: https://doi.org/10.1007/s00106-017-0362-8

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