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Sepsis

Wissen für die Praxis

Sepsis

Putting knowledge into practice

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Zusammenfassung

Sepsis ist eine komplexe systemische Entzündungsreaktion in Folge einer Infektion und muss als ein medizinischer Notfall behandelt werden. Oft wird jedoch die Diagnose verzögert gestellt, obwohl gerade die schnelle zielgerichtete Kreislauftherapie und die Therapie mit Antibiotika innerhalb der ersten Stunden die Letalität deutlich senken kann. Im vorliegenden Beitrag werden die wesentlichen Punkte zur Pathophysiologie, Diagnose und Therapie zusammengefasst.

Abstract

Sepsis is a complex systemic inflammatory reaction in response to an infection and must be treated as an emergency. The diagnosis of sepsis is often delayed even though early goal-directed resuscitation and therapy with antibiotics within the first hours can reduce sepsis-related mortality. This article presents the most important points concerning the pathophysiology, diagnosis and therapy of sepsis.

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Danksaguung

Diese Arbeit wurde durch das Bundesministerium für Bildung und Forschung (BMBF) gefördert (Förderkennzeichen 01EO1002).

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Der korrespondierende Autor gibt für sich und seine Koautoren an, dass kein Interessenkonflikt besteht.

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Authors and Affiliations

  1. Klinik für Anästhesiologie und Intensivtherapie, Universitätsklinikum Jena, Erlanger Allee 101, 07747, Jena, Deutschland

    S.N. Stehr, C.S. Hartog &  K. Reinhart

  2. Integriertes Forschungs- und Behandlungszentrum Sepsis und Sepsisfolgen, Universitätsklinikum Jena, Jena, Deutschland

    S.N. Stehr, I. Woest & C.S. Hartog

Authors
  1. S.N. Stehr
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  2. I. Woest
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  3. C.S. Hartog
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  4. K. Reinhart
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Corresponding author

Correspondence to K. Reinhart.

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Stehr, S., Woest, I., Hartog, C. et al. Sepsis. Internist 54, 63–74 (2013). https://doi.org/10.1007/s00108-012-3192-5

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  • DOI: https://doi.org/10.1007/s00108-012-3192-5

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