Skip to main content

Advertisement

SpringerLink
Log in

Urodynamic study and quality of life in patients with fibromyalgia and lower urinary tract symptoms

  • Original Article
  • Published:
International Urogynecology Journal Aims and scope Submit manuscript

Abstract

The aim of this study was to evaluate clinical and urodynamic observations on women with fibromyalgia (FM) and lower urinary tract symptoms (LUTS). Fifty-one patients with FM and LUTS and 50 patients with LUTS without FM answered questions about urinary symptoms and also two questionnaires about quality of life measures: “Medical Outcomes Study 36-Item Short-Form Health Survey” and “King's Health Questionnaire”. The urodynamic parameters evaluated were the following: maximum cystometric capacity, urine loss due to cough, Valsalva leak point pressure, and detrusor overactivity (DO). The groups were homogeneous concerning age, parity, body mass index, and genital prolapse. Symptoms such as increase of urinary frequency (p = 0.007) and urge urinary incontinence (p = 0.004) were statistically more common in the FM group. DO was the statistically most common urodynamic observation in patients with FM (p = 0.02). Regarding the questionnaires about quality of life, the patients with fibromyalgia and LUTS had the worst results in all fields. In conclusion, patients with FM and LUTS have detrusor overactivity more often as well as an increase of urinary frequency, contributing to the quality of life worsening.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Abbreviations

FM:

fibromyalgia

LUTS:

lower urinary tract symptoms

DO:

detrusor overactivity

References

  1. Pongratz DE, Sievers M (2000) Fibromyalgia—symptom or diagnosis: a definition of the position. Scand J Rheumatol 29:3–7

    Article  Google Scholar 

  2. White KP, Harth M (2001) Classification, epidemiology, and natural history of fibromyalgia. Curr Pain Headache Rep 5:320–329

    Article  PubMed  Google Scholar 

  3. Ang D, Wilke W (1999) Diagnosis, etiology and therapy of fibromyalgia. Comp Ther 25:221–227

    Google Scholar 

  4. Littlejohn GO (2004) Balanced treatments for fibromyalgia. Arthritis Rheum 9:2725–2729

    Google Scholar 

  5. Yunnus M, Masi AT, Calabro J et al (1981) Primary fibromyalgia (fibrositis): clinical study of 50 patients with matched normal controls. Semin Arthritis Rheum 26:817–824

    Google Scholar 

  6. Eich W, Hartmann M, Müller A, Fischer H (2000) The role of psychosocial factors in fibromyalgia syndrome. Scand J Rheumatol 29:30–31

    Article  Google Scholar 

  7. Fietta P (2004) Fibromyalgia: state of the art. Minerva Med 95:35–52

    PubMed  CAS  Google Scholar 

  8. Elam M, Johansson G, Wallin BG (1992) Do patient with primary fibromyalgia have an altered muscle sympathetic nerve activity? Pain 48:371–375

    Article  PubMed  Google Scholar 

  9. Vaeroy H, Helle R, Foore O, Kass E, Terenius L (1988) Elevated CSF levels of substance P and high incidence of Raynaud phenomenon in patients with fibromyalgia: new features for diagnosis. Pain 32:21–26

    Article  PubMed  Google Scholar 

  10. Ng SC (1992) The fibromyalgia syndrome. Singapore Med J 33:294–295

    PubMed  Google Scholar 

  11. Clauw DJ (1995) Fibromyalgia: more than just musculoskeletal disease. Am Fam Physician 52:843–851

    PubMed  Google Scholar 

  12. Clauw DJ, Schmidt M, Radulovic D, Singer A, Katz P, Bresette J (1997) The relationship between fibromyalgia and interstitial cystitis. J Psychiatr Res 31:125–131

    Article  PubMed  Google Scholar 

  13. Wallace DJ (1990) Genitourinary manifestations of fibrositis: an increased association with the female urethral syndrome. J Rheumatol 17:238–239

    PubMed  Google Scholar 

  14. Stormorken H, Brosstad F (2005) Hypping vannlating-viktig diagnostisk markor ved fibromyalgi. Tidsskr Nor Laegeforen 125:17–19

    PubMed  Google Scholar 

  15. Wolfe F, Smythe HA, Yunus MB, Bennet RM, Bombardier C, Goldenberg DL et al (1990) The American College of Rheumatology 1990 criteria for the classification of fibromyalgia: report of the multicenter criteria committee. Arthritis Rheum 33:160–172

    Article  PubMed  Google Scholar 

  16. Abrams P, Cardozo L, Fall M et al (2002) The standardization of terminology of lower urinary tract function: report from the Standardization Sub-committee of the International Continence Society. Am J Obstet Gynecol 187:116–126

    Article  PubMed  Google Scholar 

  17. Ware JE, Sherbourne CD (1992) The MOS 36-Item Short-Form Health Survey (SF-36): conceptual framework and item selection. Med Care 30:473–483

    PubMed  Google Scholar 

  18. Kelleher CJ, Cardozo LD, Khullar V, Salvatore S (1997) A new questionnaire to assess the quality of life of urinary incontinent women. Br J Obstet Gynaecol 104:1374–1379

    PubMed  Google Scholar 

  19. Tamanini JTN, Dáncona CAL, Botega NJ, Netto NR Jr (2003) Validation of the Portuguese version of the King's Health Questionnaire for urinary incontinent women. Rev Saúde Pública 37:203–211

    Article  PubMed  Google Scholar 

  20. Heesakkers JPFA, Vriesema LJ (2005) The role of urodynamics in the treatment of lower urinary tract symptoms in women. Current Opin in Urol 15:215–221

    Google Scholar 

  21. Sekido N, Hinotsu S, Kawai K, Shimazui T, Akaza H (2006) How many uncomplicated male and female overactive bladder patients reveal detrusor overactivity during urodynamic study? Int J Urol 13:1276–1279

    Article  PubMed  Google Scholar 

  22. Robertson AS, Griffiths CJ, Ramsden PD et al (1994) Bladder function in healthy volunteers: ambulatory monitoring and conventional urodynamics. Brit J Urol 73:242–249

    Article  PubMed  Google Scholar 

  23. Aaron LA, Buchwald D (2001) A review of the evidence for overlap among unexplained clinical conditions. Ann Intern Med 134:868–881

    PubMed  Google Scholar 

  24. Koskimäki J, Hakama M, Huhtala H, Tammela TLJ (2001) Association of non-urological diseases with lower urinary tract symptoms. Scand J Urol Nephrol 35:377–381

    PubMed  Google Scholar 

  25. Sarzi-Puttini P, Atzeni F, Fiorini T, Panni B, Randisi G, Turiel M, Carrabba M (2003) Validation of an Italian version of the Fibromyalgia Impact Questionnaire (FIQ-I). Clin Exp Rheumatol 21:459–464

    PubMed  Google Scholar 

  26. Quarto G, Autorino R, Gallo A, De Sio M, D, 'Armiento M, Perdonà S, Damiano R (2007) Quality of life in women with multiple sclerosis and overactive bladder syndrome. Int Urogynecol J Pelvic Floor Dysfunct 18:189–194

    PubMed  Google Scholar 

  27. Khaled SM, Elhilali M (2003) Role of 5-HT receptors in treatment of overactive bladder. Drugs Today 39:599–607

    Article  PubMed  CAS  Google Scholar 

  28. Kershen RT, Hsiech M (2004) Preview of new drugs for overactive bladder and incontinence: darifenacin, solifenacin, trospium, and duloxetine. Curr Urol Rep 5:359–367

    Article  PubMed  Google Scholar 

  29. Mc Cormack PL, Keating GM (2004) Duloxetine: in stress urinary incontinence. Drugs 64:2567–2573

    Google Scholar 

  30. Ghoniem GM, Van Leeuwes JS, Freeman RM, Zhao YD, Yalcin I, Bump RC (2005) A randomized controlled trial of duloxetine alone, pelvic floor muscle training alone, combined treatment and no active treatment in women with stress urinary incontinence. J Urol 173:1647–1653

    Article  PubMed  Google Scholar 

Download references

Conflicts of interest

None.

Author information

Authors and Affiliations

  1. Sector of Urogynecology, Federal University of São Paulo, São Paulo, Brazil

    Maíta Poli de Araújo, Claudia Cristina Takano, Emerson de Oliveira, Marair Gracio Ferreira Sartori & Manoel Joâo Batista Castello Girão

  2. Discipline of Rheumatology, Federal University of São Paulo, São Paulo, Brazil

    Alex Carvalho Faria & Daniel Feldman Pollak

Authors
  1. Maíta Poli de Araújo
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Alex Carvalho Faria
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Claudia Cristina Takano
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Emerson de Oliveira
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Marair Gracio Ferreira Sartori
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Daniel Feldman Pollak
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Manoel Joâo Batista Castello Girão
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Maíta Poli de Araújo.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Araújo, M.P.d., Faria, A.C., Takano, C.C. et al. Urodynamic study and quality of life in patients with fibromyalgia and lower urinary tract symptoms. Int Urogynecol J 19, 1103–1107 (2008). https://doi.org/10.1007/s00192-008-0577-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00192-008-0577-z

Keywords

Search

Navigation