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Hospital burden of vertebral fractures in France: influence of vertebroplasty

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Abstract

Summary

We described the whole population of patients hospitalized for vertebral fractures in France in 2009. Only 6.4 % of them were operated by vertebroplasty; these patients were younger and healthier than non-operated patients.

Introduction

This study aims to describe the burden of vertebral fractures from the 2009 French Hospital National Database in acute care in people aged 60 years and over, with or without vertebroplasty.

Methods

All stays due to nonmalignant and nontraumatic vertebral fractures as primary cause were selected. Patients’ characteristics were described and compared between patients with or without vertebroplasty. The in-patient mortality was compared to the one related to hip and upper humerus fracture in patients hospitalized during the same year.

Results

In 2009, 13,624 patients were hospitalized for vertebral fracture. Men accounted for 29.3 % of cases. Length of stay was 9.6 ± 8.2 days, higher in patients with at least one comorbidity than in patients without (11.2 ± 8.6 and 7.8 ± 7.2 days, respectively). The in-patient mortality was 0.9 %; it was 3.8 and 1.1 % for hip and upper humerus fractures, respectively. Vertebroplasty was performed in 6.4 % of them. Patients with vertebroplasty were younger (mean age of 75 ± 8 versus 79 ± 9 years), had a less duration of stay (7 ± 7.5 versus 9.8 ± 8.2 days), less comorbidities (at least one comorbidity, 45 versus 54 %), and less in-patient mortality (0.1 versus 0.9 %). Rehospitalization for vertebral fracture occurred in 9 and 6 % of the patient with and without vertebroplasty.

Conclusion

This is the first French study assessing the national burden of vertebral fractures based on hospital data. In-hospital death rate is lower in patients with vertebroplasty, who are younger and have less comorbidities than the general population with vertebral fractures.

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References

  1. O’Neill TW, Cockerill W, Matthis C et al (2004) Back pain, disability, and radiographic vertebral fracture in European women: a prospective study. Osteoporos Int 15:760–765

    Article  PubMed  Google Scholar 

  2. Fechtenbaum J, Cropet C, Kolta S, Horlait S, Orcel P, Roux C (2005) The severity of vertebral fractures and health-related quality of life in osteoporotic postmenopausal women. Osteoporos Int 16:2175–2179

    Article  PubMed  CAS  Google Scholar 

  3. Center JR, Bliuc D, Nguyen TV et al (2007) Risk of subsequent fracture after low-trauma fracture in men and women. JAMA 297:387–394

    Article  PubMed  CAS  Google Scholar 

  4. Center JR, Nguyen TV, Schneider D, Sambrook PN, Eisman JA (1999) Mortality after all major types of osteoporotic fracture in men and women: an observational study. Lancet 353:878–882

    Article  PubMed  CAS  Google Scholar 

  5. Kado DM, Browner WS, Palermo L, Nevitt MC, Genant HK, Cummings SR (1999) Vertebral fractures and mortality in older women: The Study of Osteoporotic Fracture. Arch Intern Med 159:1215–1220

    Article  PubMed  CAS  Google Scholar 

  6. Ensrud KE, Thompson DE, Cauley JA et al (2000) Prevalent vertebral deformities predict mortality and hospitalization in older women with low bone mass. J Am Geriatr Soc 48:241–249

    PubMed  CAS  Google Scholar 

  7. Ismail AA, O’Neill TW, Cooper C et al (1998) Mortality associated with vertebral deformity in men and women: results from the European Prospective Osteoporosis Study (EPOS). Osteoporos Int 8:291–297

    Article  PubMed  CAS  Google Scholar 

  8. Cauley JA, Thompson DE, Ensrud KC, Scott JC, Black D (2000) Risk of mortality following clinical fractures. Osteoporos Int 11:556–561

    Article  PubMed  CAS  Google Scholar 

  9. Bliuc D, Nguyen ND, Milch VE et al (2009) Mortality risk associated with low-trauma osteoporotic fracture and subsequent fracture in men and women. JAMA 301:513–521

    Article  PubMed  CAS  Google Scholar 

  10. Kanis JA, Oden A, Johnell O, De Laet C, Jonsson B (2004) Excess mortality after hospitalisation for vertebral fracture. Osteoporos Int 15:108–112

    Article  PubMed  Google Scholar 

  11. Roux C, Fechtenbaum J, Kolta S, Said-Nahal R, Briot K, Benhamou CL (2010) Prospective assessment of thoracic kyphosis in postmenopausal women with osteoporosis. J Bone Miner Res 25:362–368

    Article  PubMed  Google Scholar 

  12. Bouza C, Lopez T, Palma M, Amate JM (2007) Hospitalized osteoporotic vertebral fractures in Spain: analysis of the national hospital discharge registry. Osteoporos Int 18:649–657

    Article  PubMed  CAS  Google Scholar 

  13. Kallmes DF, Comstock BA, Heagerty PJ et al (2009) A randomized trial of vertebroplasty for osteoporotic spinal fractures. N Engl J Med 361:569–579

    Article  PubMed  CAS  Google Scholar 

  14. Buchbinder R, Osborne RH, Ebeling PR et al (2009) A randomized trial of vertebroplasty for painful osteoporotic vertebral fractures. N Engl J Med 361:557–568

    Article  PubMed  CAS  Google Scholar 

  15. Edidin AA, Ong KL, Lau E, Kurtz SM (2011) Mortality risk for operated and non-operated vertebral fracture patients in the Medicare population. J Bone Miner Res. doi:10.1002/jbmr.353

  16. Zampino JM, White AP, McGuire KJ (2010) Comparison of 5766 vertebral compression fractures treated with or without kyphoplasty. Clin Orthop Relat Res 468:1773–1780

    Article  Google Scholar 

  17. Maravic M, Le Bihan C, Richard JB et al (2005) Incidence and cost of osteoporotic fractures in France during. A methodological approach by the national hospital database. Osteoporos Int 16(12):1475–1480

    Article  PubMed  Google Scholar 

  18. Maravic M, Taupin P, Landais P, Roux C (2011) Change in hip fracture incidence over the last six years in France. Osteoporos Int 22:797–801

    Article  PubMed  CAS  Google Scholar 

  19. Papaioannou A, Adachi JD, Parkinson W, Stephenson G, Bedard M (2001) Lengthy hospitalization associated with vertebral fractures despite control for comorbid conditions. Osteoporos Int 12:870–874

    Article  PubMed  CAS  Google Scholar 

  20. Phillips S, Fox N, Jacobs J, Wright WE (1986) The direct medical costs of osteoporosis for American women aged 45 and older. Bone 9:271–279

    Article  Google Scholar 

  21. Johnell O, Gullberg B, Kanis JA (1997) The hospital burden of vertebral fracture in Europe: a study of national register sources. Osteoporos Int 7:138–144

    Article  PubMed  CAS  Google Scholar 

  22. McDonald RJ, Achenbach SJ, Atkinson EJ, Gray LA, Cloft HJ, Melton LJ III, Kallmes DF (2011) Mortality in the vertebroplasty population. Am J N Rad 32:1818–1823

    CAS  Google Scholar 

  23. Lee YK, Jang S, Jang S, Lee HJ, Park C, Ha YC, Kim DY (2012) Mortality after vertebral fracture in Korea. Analysis of the National Claim Registry. Osteoporos Int 23:1859–1865

    Article  PubMed  Google Scholar 

  24. Gehlbach SH, Bigelow C, Heimisdoltir M et al (2000) Recognition of vertebral fractures in a clinical setting. Osteoporos Int 11:577–582

    Article  PubMed  CAS  Google Scholar 

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Acknowledgments

This work is supported by the Collège Français des Médecins Rhumatologues (CFMR).

Conflicts of interest

None.

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Authors and Affiliations

  1. Département d’Information Médicale, Hôpital Léopold Bellan, 19-21 rue Vercingétorix, 75674, Paris Cedex 14, France

    M. Maravic

  2. Biostatistique et Informatique médicale, Hôpital Necker, Paris, France

    P. Taupin

  3. Hôpital Cochin, Département de Rhumatologie, Université Paris Descartes, Paris, France

    C. Roux

Authors
  1. M. Maravic
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  2. P. Taupin
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  3. C. Roux
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Correspondence to M. Maravic.

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Maravic, M., Taupin, P. & Roux, C. Hospital burden of vertebral fractures in France: influence of vertebroplasty. Osteoporos Int 24, 2001–2006 (2013). https://doi.org/10.1007/s00198-012-2264-7

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  • DOI: https://doi.org/10.1007/s00198-012-2264-7

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