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Does a different dose of gamma irradiation have the same effect on five different types of tendon allografts? — a biomechanical study

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Abstract

Introduction

The goals of our study were to evaluate the biomechanical differences between five tendons and the changes in biomechanical properties caused by irradiation.

Methods

Achilles, quadriceps, semitendinosus + gracilis (STG), tibialis anterior (TA) and the peroneus longus (PL) were harvested from 30 donors. Group A contained 50 tendons without gamma irradiation. The groups were irradiated with a dose of 21 kGy (group B 50 tendons) and with a dose of 42 kGy (group C 50 tendons). The grafts were soaked in a radio-protectant solution and frozen at −80 °C. Cyclic loading tests were performed followed by load to failure tests. Young modulus of elasticity, maximum force, strain at tensile strength and strain at rupture were calculated.

Results

The Achilles tendons had significantly lower Young modulus than the TA (p = 0.0036) in group A. The Achilles showed significantly lower than PL (p = 0.000042) and TA (p = 0.00142) in group B and C. The quadriceps and the ST (p = 0.0037) provided poorer values than the TA (p = 0.0432) in group C. We found no difference in maximum loads among the tendons in group A. The maximum load of the Achilles and quadriceps showed better results than the PL (p = 0.0016), (p = 0.0018) and the STG (p = 0.0066), (p = 0.0019) in group C. The TA had similar results like the Achilles and quadriceps.

Discussion and conclusions

The vulnerability of gamma irradiation of TA was less than Achilles and quadriceps tendons.

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Acknowledgements

This work was supported by the Hungarian Scientific Research Found (OTKA101070 and 116189 grants).

Gábor Szebényi acknowledges the financial support received through János Bolyai Scholarship of the Hungarian Academy of Sciences.

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Authors and Affiliations

  1. Department of Orthopedics and Traumatology, Uzsoki Hospital, Uzsoki Street 29-41, 1145, Budapest, Hungary

    Gyorgy Hangody, Bence Abonyi, László Hangody & Károly Pap

  2. Cooperation Research Center for Biomechanics, Budapest University of Technology and Economics, Bertalan Lajos Street 2, 1111, Budapest, Hungary

    Gábor Szebényi & Rita Kiss

  3. Department of Traumatology, Semmelweis University, Uzsoki Street 29-41, 1145, Budapest, Hungary

    László Hangody & Károly Pap

Authors
  1. Gyorgy Hangody
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  2. Gábor Szebényi
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  3. Bence Abonyi
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  4. Rita Kiss
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  5. László Hangody
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  6. Károly Pap
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Correspondence to Károly Pap.

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No benefits in any form have been received or will be received from a commercial party related directly or indirectly to the subject of this article.

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There is no other funding source than that mentioned in the acknowledgment.

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This article does not contain any studies with human participants or animals performed by any of the authors.

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Informed consent was obtained from all individual participants included in the study.

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Hangody, G., Szebényi, G., Abonyi, B. et al. Does a different dose of gamma irradiation have the same effect on five different types of tendon allografts? — a biomechanical study. International Orthopaedics (SICOT) 41, 357–365 (2017). https://doi.org/10.1007/s00264-016-3336-7

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  • DOI: https://doi.org/10.1007/s00264-016-3336-7

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