References
Falini B, Mecucci C, Tiacci E, Alcalay M, Rosati R, Pasqualucci L et al (2005) Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype. N Engl J Med 352:254–266
Schnittger S, Schoch C, Kern W, Mecucci C, Tschulik C, Martelli MF et al (2005) Nucleophosmin gene mutations are predictors of favorable prognosis in acute myelogenous leukemia with a normal karyotype. Blood 106:3733–3739
Boissel N, Renneville A, Biggio V, Philippe N, Thomas X, Cayuela JM et al (2005) Prevalence, clinical profile, and prognosis of NPM mutations in AML with normal karyotype. Blood 106:3618–3620
Verhaak RG, Goudswaard CS, van Putten W, Bijl MA, Sanders MA, Hugens W et al (2005) Mutations in nucleophosmin (NPM1) in acute myeloid leukemia (AML): association with other gene abnormalities and previously established gene expression signatures and their favorable prognostic significance. Blood 106:3747–3754
Dohner K, Schlenk RF, Habdank M, Scholl C, Rucker FG, Corbacioglu A et al (2005) Mutant nucleophosmin (NPM1) predicts favorable prognosis in younger adults with acute myeloid leukemia and normal cytogenetics: interaction with other gene mutations. Blood 106:3740–3746
Suzuki T, Kiyoi H, Ozeki K, Tomita A, Yamaji S, Suzuki R et al (2005) Clinical characteristics and prognostic implications of NPM1 mutations in acute myeloid leukemia. Blood 106:2854–2861
Chou WC, Tang JL, Lin LI, Yao M, Tsay W, Chen CY, Wu SJ et al (2006) Nucleophosmin mutations in de novo acute myeloid leukemia: the age-dependent incidences and the stability during disease evolution. Cancer Res 66:3310–3316
Rappaport H (1966) Tumors of the hematopoietic system: In: Atlas of tumor pathology, section 3, fascicle 8. Armed Forces Institute of Pathology, Washington, DC, pp 241–243
Swirski DM, Li YS, Matthews JG, Flemans RJ, Rees JK, Hayhoe FG (1984) 8;21 Translocation in acute granulocyte leukaemia: cytological, cytochemical and clinical features. Br J Haematol 56:199–213
Bolli N, Galimberti S, Martelli MP, Tabarrini A, Roti G, Mecucci C et al (2006) Cytoplasmic nucleophosmin in myeloid sarcoma occurring 20 years after diagnosis of acute myeloid leukaemia. Lancet Oncol 7:350–352
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Scholl, S., Lüftner, J., Mügge, LO. et al. Sustained expression of nucleophosmin (NPM1) mutation at late relapse presenting as isolated myeloid sarcoma in a patient with acute myeloid leukemia. Ann Hematol 86, 763–765 (2007). https://doi.org/10.1007/s00277-007-0323-5
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00277-007-0323-5