References
Bain BJ et al. (2008) Myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRa, PDGFRß or FGFR1. In: WHO classification of tumours of haematopoietic and lymphoid tissue, 68–73. (Lyon) Fourth Edition ed.
Ogbogu PU, Bochner BS, Butterfield JH, Gleich GJ, Huss-Marp J, Kahn JE et al (2009) Hypereosinophilic syndrome: a multicenter, retrospective analysis of clinical characteristics and response to therapy. J Allergy Clin Immunol 124(6):1319–1325, e3
Cools J, DeAngelo DJ, Gotlib J, Stover EH, Legare RD, Cortes J et al (2003) A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome. N Engl J Med 348(13):1201–1214
Vandenberghe P, Wlodarska I, Michaux L, Zachee P, Boogaerts M, Vanstraelen D et al (2004) Clinical and molecular features of FIP1L1-PDFGRA (+) chronic eosinophilic leukemias. Leukemia 18(4):734–742
Pardanani A, Brockman SR, Paternoster SF, Flynn HC, Ketterling RP, Lasho TL et al (2004) FIP1L1-PDGFRA fusion: prevalence and clinicopathologic correlates in 89 consecutive patients with moderate to severe eosinophilia. Blood 104(10):3038–3045
Roche-Lestienne C, Lepers S, Soenen-Cornu V, Kahn JE, Lai JL, Hachulla E et al (2005) Molecular characterization of the idiopathic hypereosinophilic syndrome (HES) in 35 French patients with normal conventional cytogenetics. Leukemia 19(5):792–798
Erben P, Gosenca D, Muller MC, Reinhard J, Score J, Del Valle F et al (2010) Screening for diverse PDGFRA or PDGFRB fusion genes is facilitated by generic quantitative reverse transcriptase polymerase chain reaction analysis. Haematologica 95(5):738–744
Metzgeroth G, Walz C, Erben P, Popp H, Schmitt-Graeff A, Haferlach C et al (2008) Safety and efficacy of imatinib in chronic eosinophilic leukaemia and hypereosinophilic syndrome: a phase-II study. Br J Haematol 143(5):707–715
Sakuta R, Tomita Y, Ohashi M, Nagai T, Murakami N (2007) Idiopathic hypereosinophilic syndrome complicated by central sinovenous thrombosis. Brain Dev 29(3):182–184
Kobayashi M, Komatsu N, Kuwayama Y, Bandobashi K, Kubota T, Uemura Y et al (2007) Idiopathic hypereosinophilic syndrome presenting acute abdomen. Intern Med 46(10):675–678
Jang KA, Lim YS, Choi JH, Sung KJ, Moon KC, Koh JK (2000) Hypereosinophilic syndrome presenting as cutaneous necrotizing eosinophilic vasculitis and Raynaud’s phenomenon complicated by digital gangrene. Br J Dermatol 143(3):641–644
Kawata E, Kuroda J, Wada K, Yoshida M, Kamiuchi K, Nakayama-Harusato I et al (2007) Hypereosinophilic syndrome accompanied by Buerger’s disease-like femoral arterial occlusions. Intern Med 46(23):1919–1922
Author information
Authors and Affiliations
Corresponding author
Additional information
Thomas Klag and Thomas Schnetzke have contributed equally to this work.
Rights and permissions
About this article
Cite this article
Klag, T., Schnetzke, U., Benz, R. et al. Leriche’s syndrome and Löffler endocarditis in a 30-year-old patient presenting with hypereosinophilic syndrome. Ann Hematol 91, 139–141 (2012). https://doi.org/10.1007/s00277-011-1232-1
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00277-011-1232-1