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Glia in Drosophila behavior

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Abstract

Glial cells constitute about 10 % of the Drosophila nervous system. The development of genetic and molecular tools has helped greatly in defining different types of glia. Furthermore, considerable progress has been made in unraveling the mechanisms that control the development and differentiation of Drosophila glia. By contrast, the role of glia in adult Drosophila behavior is not well understood. We here summarize recent work describing the role of glia in normal behavior and in Drosophila models for neurological and behavioral disorders.

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Acknowledgments

The authors received financial support of VIB, IWT and FWO (grants G.0654.08 and G.0789.14). We are grateful to the anonymous reviewers for their critical input that helped improve this review.

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  1. Laboratory of Behavioral and Developmental Genetics VIB Center for the Biology of Disease, Center for Human Genetics, KULeuven, O&N IV Herestraat 49, Box 602, 3000, Louvain, Belgium

    L. Zwarts, F. Van Eijs & P. Callaerts

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  1. L. Zwarts
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  2. F. Van Eijs
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  3. P. Callaerts
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Correspondence to P. Callaerts.

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Zwarts, L., Van Eijs, F. & Callaerts, P. Glia in Drosophila behavior. J Comp Physiol A 201, 879–893 (2015). https://doi.org/10.1007/s00359-014-0952-9

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