Skip to main content
SpringerLink
Log in

Malignant struma ovarii with a focus of papillary thyroid cancer: a case report

  • Case Report
  • Published:
Archives of Gynecology and Obstetrics Aims and scope Submit manuscript

Abstract

Struma ovarii is a rare form of ovarian neoplasm and its malignant transformation is even rarer. Because of its rarity, there is no consensus about its diagnosis and management in the literature. A 53-year-old woman with left adnexial mass underwent total abdominal hysterectomy with bilateral salpingo-oopherectomy. Postoperatively, she was diagnosed with a malignant struma ovarii. Postoperative thyroid ultrasonography revealed a 0.5-cm solid nodule in the thyroid gland and total thyroidectomy was done. Pathology report was nodular hyperplasia of benign character. She is currently disease-free for 1 year but long-term follow-up with thyroglobulin levels is necessary due to reports of increasing recurrence rates.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

References

  1. Willemse PH, Oosterhuis JW, Aalders JG, Piers DA, Sleijfer DT, Vermey A, Doorenbos H (1987) Malignant struma ovarii treated by ovariectomy, thyroidectomy, and 131I administration. Cancer 60(2):178–182

    Article  PubMed  CAS  Google Scholar 

  2. Kabukcuoglu F, Baksu A, Yılmaz B, Aktumen A, Evren I (2002) Malignant struma ovarii. Pathol Oncol Res 8(2):145–147

    Article  PubMed  Google Scholar 

  3. Zakhem A, Aftimos G, Kreidy R, Salem P (1990) Malignant struma ovarii: report of two cases and selected review of the literature. J Surg Oncol 43:61–65

    Article  PubMed  CAS  Google Scholar 

  4. Berghella V, Ngadiman S, Rosenberg H, Hoda S, Zuna R (1997) Malignant struma ovarii. A case report and review of the literature. Gynecol Obstet Invest 43(1):68–72

    Article  PubMed  CAS  Google Scholar 

  5. Devaney K, Synder R, Norris H, Tavassoli F (1993) Proliferative and histologically malignant struma ovarii: a clinicopathologic study of 54 cases. Int J Gynecol Pathol 12(4):333–343

    PubMed  CAS  Google Scholar 

  6. Rosenblum N, LiVolsi V, Edmonds P, Mikuta J (1989) Malignant struma ovarii. Gynecol Oncol 32:224–227

    Article  PubMed  CAS  Google Scholar 

  7. Kostoglou-Athanassiou I, Lekka-Katsouli I, Gogou L, Papagrigoriou L, Chatonides I, Kaldrymides P (2002) Malignant struma ovarii: report of a case and review of the literature. Horm Res 58(1):34–38

    Article  PubMed  CAS  Google Scholar 

  8. Checrallah A, Medlej R, Sade C, Khayat G, Halaby G (2001) Malignant struma ovarii: an unusual presentation. Thyroid 11(9):889–892

    Article  PubMed  CAS  Google Scholar 

  9. DeSimone C, Lele S, Modesitt S (2003) Malignant struma ovarii: a case report and analysis of cases reported in the literature with focus on survival and I131 therapy. Gynecol Oncol 89(3):543–548

    Article  PubMed  Google Scholar 

  10. Gonzales A, Kaufman RH, Braungardt CD et al (1963) Adenocarcinoma of thyroid arising in struma ovarii (malignant struma ovarii) Report of two cases and review of the literature. Obstet Gynecol 21:567–576

    Google Scholar 

  11. Nogales FF (1995) Germ cell tumours of the ovary. In: Fox H, Wells M (eds) Obstetrical and Gynecological Pathology, 4th edn. Churchill Livingstone, New York, pp 847–896

    Google Scholar 

  12. Szyfelbein WM, Young RH, Scully RE (1995) Struma ovarii simulating ovarian tumors of other types. A report of 30 cases. Am J Surg Pathol 19(1):21–29

    Article  PubMed  CAS  Google Scholar 

  13. Pardo-Mindan FJ, Vazquez JJ (1983) Malignant struma ovarii. Light and electron microscopic study. Cancer 51:337–343

    Article  PubMed  CAS  Google Scholar 

  14. Chan S, Farrell K (2001) Metastatic thyroid carcinoma in the presence of struma ovarii. Med J Aust 175(7):373–374

    PubMed  CAS  Google Scholar 

  15. Dardik RB, Dardik M, Westra W, Montz FJ (1999) Malignant struma ovarii: two case reports and a review of the literature. Gynecol Oncol 73(3):447–451

    Article  PubMed  CAS  Google Scholar 

  16. Makani S, Kim W, Gaba AR (2004) Struma Ovarii with a focus of papillary thyroid cancer: a case report and review of the literature. Gynecol Oncol 94(3):835–839

    Article  PubMed  Google Scholar 

  17. O’Connell M, Fisher C, Harmer C (1990) Malignant struma ovarii: presentation and management. Br J Radiol 63(749):360–363

    Article  PubMed  CAS  Google Scholar 

  18. Rose PG, Arafah B, Abdul-Karim F (1998) Malignant struma ovarii: recurrence and response to treatment monitored by thyroglobulin levels. Gynecol Oncol 70:425–427

    Article  PubMed  CAS  Google Scholar 

  19. Lubin E, Mechlis-Frish Zata S, Shimoni A, Segal K et al (1994) Serum thyroglobulin and iodine-131 whole-body scan in the diagnosis and assessment of treatment for metastatic differentiated thyroid carcinoma. J Nucl Med 35(2):257–262

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Obstetrics and Gynecology, Dr. Zekai Tahir Burak Woman Health Education and Research Hospital, Akat sok. No: 3/10, 06500, Cebeci/Ankara, Turkey

    Melike Doganay, Tayfun Gungor, Sabri Cavkaytar & Leyla Mollamahmutoglu

  2. Department of Pathology, Dr. Zekai Tahir Burak Woman Health Education and Research Hospital, Ankara, Turkey

    Levent Sirvan

Authors
  1. Melike Doganay
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Tayfun Gungor
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Sabri Cavkaytar
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Levent Sirvan
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Leyla Mollamahmutoglu
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Sabri Cavkaytar.

Additional information

This study was accepted as a poster presentation at the VII International Congress of the Turkish-German Gynecological Association, Antalya, Turkey, 16–20 May 2007.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Doganay, M., Gungor, T., Cavkaytar, S. et al. Malignant struma ovarii with a focus of papillary thyroid cancer: a case report. Arch Gynecol Obstet 277, 371–373 (2008). https://doi.org/10.1007/s00404-007-0466-6

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00404-007-0466-6

Keywords

Search

Navigation