Skip to main content

Advertisement

Log in

Identity of pigmented subretinal cells in age-related macular degeneration

  • Letter to the Editor
  • Published:
Graefe's Archive for Clinical and Experimental Ophthalmology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

References

  1. Rudolf M, Vogt SD, Curcio CA, Huisingh C, McGwin G Jr, Wagner A, Grisanti S, Read RW (2013) Histologic basis of variations in retinal pigment epithelium autofluorescence in eyes with geographic atrophy. Ophthalmology 120:821–828

    Article  PubMed  PubMed Central  Google Scholar 

  2. Zanzottera EC, Messinger JD, Ach T, Smith RT, Curcio CA (2015) Subducted and melanotic cells in advanced age-related macular degeneration are derived from retinal pigment epithelium. Invest Ophthalmol Vis Sci 56:3269–3278

    Article  PubMed  PubMed Central  Google Scholar 

  3. Schamburg-Lever G, Lever WF (1973) Electron microscopy of incontinentia pigmenti. J Investig Dermatol 61:151–158

    Article  CAS  PubMed  Google Scholar 

  4. Fineman MS, Eagle RC, Shields JA, Shields CL, De Potter P (1998) Melanocytomalytic glaucoma in eyes with necrotic iris melanocytoma. Ophthalmology 105:492–496

    Article  CAS  PubMed  Google Scholar 

  5. Sennlaub F, Auvynet C, Calippe B, Lavalette S, Poupel L, Hu SJ, Dominguez E, Camelo S, Levy O, Guyon E (2013) CCR2+ monocytes infiltrate atrophic lesions in age-related macular disease and mediate photoreceptor degeneration in experimental subretinal inflammation in Cx3cr1 deficient mice. EMBO Mol Med 5:1775–1793

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Owaribe K, Kartenbeck J, Rungger-Brändle E, Franke WW (1988) Cytoskeletons of retinal pigment epithelial cells: interspecies differences of expression patterns indicate independence of cell function from the specific complement of cytoskeletal proteins. Cell Tissue Res 254:301–315

    Article  CAS  PubMed  Google Scholar 

  7. Kasper M, Moll R, Stosiek P, Karsten U (1988) Patterns of cytokeratin and vimentin expression in the human eye. Histochemistry 89:369–377

    Article  CAS  PubMed  Google Scholar 

  8. Grossniklaus HE, Ling JX, Wallace TM, Dithmar S, Lawson DH, Cohen C, Elner VM, Elner SG, Sternberg P Jr (2002) Macrophage and retinal pigment epithelium expression of angiogenic cytokines in choroidal neovascularization. Mol Vis 8:119–126

    CAS  PubMed  Google Scholar 

  9. Shepard JL, Zon LI (2000) Developmental derivation of embryonic and adult macrophages. Curr Opin Hematol 7:3–8

    Article  CAS  PubMed  Google Scholar 

  10. Klimanskaya I, Hipp J, Rezai KA, West M, Atala A, Lanza R (2004) Derivation and comparative assessment of retinal pigment epithelium from human embryonic stem cells using transcriptomics. Cloning Stem Cells 6:217–245

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Eleonora M. Lad.

Ethics declarations

Financial disclosure

None to report

Conflict of interest

None to report

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Lad, E.M., Cousins, S.W. & Proia, A.D. Identity of pigmented subretinal cells in age-related macular degeneration. Graefes Arch Clin Exp Ophthalmol 254, 1239–1241 (2016). https://doi.org/10.1007/s00417-015-3249-y

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00417-015-3249-y

Keywords

Navigation