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Preserving infrapyloric vein reduces postoperative gastric stasis after laparoscopic pylorus-preserving gastrectomy

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Abstract

Purpose

Laparoscopic pylorus-preserving gastrectomy (LPPG) is performed to preserve function in treating early gastric cancer. However, gastric stasis is a potential complication of LPPG that could decrease postoperative quality of life, possibly due to gastric edema of the pyloric cuff caused by venous stasis. We introduced an infrapyloric vein (IPV)-preserving LPPG (iLPPG) procedure to prevent pyloric cuff edema and thus minimize the incidence of gastric stasis and investigated the early clinical outcomes of iLPPG.

Methods

We reviewed 150 patients with gastric cancer who underwent LPPG between August 2011 and June 2013 at the Cancer Institute Hospital and analyzed postoperative complications, incidence of gastric stasis (requiring starvation longer than 72 h or an invasive treatment), and transient delayed gastric emptying (TDGE).

Results

Of the 150 patients, 56 underwent iLPPG and 94 underwent conventional LPPG without preservation of the IPV (cLPPG). Morbidity rates were 5.4% in the iLPPG group and 23.4% in the cLPPG group (P = 0.003). The incidence of both gastric stasis and TDGE was significantly lower in the iLPPG group than in the cLPPG group (0 vs. 8.5%, P = 0.03 and 0 vs. 7.4%, P = 0.046, respectively). Median postoperative stay was significantly shorter in the iLPPG group compared to the cLPPG group (9 vs. 11 days, P < 0.001, respectively).

Conclusions

Preservation of the IPV might prevent the incidence of postoperative gastric stasis after LPPG, resulting in a shorter postoperative stay.

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Authors and Affiliations

  1. Department of Gastroenterological Surgery, Gastroenterological Center, Cancer Institute Hospital, Japanese Foundation for Cancer Research, 3-10-6 Ariake, Koto-ku, Tokyo, 135-8550, Japan

    Takashi Kiyokawa, Naoki Hiki, Souya Nunobe, Michitaka Honda, Manabu Ohashi & Takeshi Sano

Authors
  1. Takashi Kiyokawa
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  2. Naoki Hiki
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  3. Souya Nunobe
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  4. Michitaka Honda
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  5. Manabu Ohashi
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  6. Takeshi Sano
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Corresponding author

Correspondence to Naoki Hiki.

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Authors’ contributions

  • Study conception and design: Takashi Kiyokawa, Naoki Hiki, and Souya Nunobe.

  • Acquisition of data: Takashi Kiyokawa, Michitaka Honda, and Manabu Ohashi.

  • Analysis and interpretation of data: Takashi Kiyokawa, Michitaka Honda, and Naoki Hiki.

  • Drafting of manuscript: Takashi Kiyokawa, Naoki Hiki, and Takeshi Sano.

  • Critical revision of manuscript: Naoki Hiki and Takeshi Sano.

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.

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Kiyokawa, T., Hiki, N., Nunobe, S. et al. Preserving infrapyloric vein reduces postoperative gastric stasis after laparoscopic pylorus-preserving gastrectomy. Langenbecks Arch Surg 402, 49–56 (2017). https://doi.org/10.1007/s00423-016-1529-6

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  • DOI: https://doi.org/10.1007/s00423-016-1529-6

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