Abstract
Background
The minimal clinically important difference (MCID) for the Gastrointestinal Quality of Life Index (GIQLI) is unknown, which limits its application and interpretation. This study aimed to estimate MCIDs for the GIQLI scores of patients after they had undergone cholecystectomy.
Methods
This study had 267 participants. All the participants completed the GIQLI and four anchor items, namely, “How would you describe your overall symptoms, emotions, physical functions, and social functions since your last visit?” The response options were “much worse,” “somewhat worse,” “same,” “somewhat better” and “much better.” The MCID was defined according to those who responded with “somewhat better.”
Results
The mean age of the participants was 57.81 ± 14.93 years, and 37.08% of the patients were women. The MCID group included 67, 78, 44, and 22 patients with MCIDs of 6.42, 6.86, 7.64 and 6.46 points respectively for scores on the symptoms, emotions, physical functions, and social functions subscales, respectively. The effect sizes of four anchors in the “somewhat better” group (0.38–0.49) exceeded those of the same group (0.25–0.38).
Conclusions
This study showed that after patients had undergone cholecystectomy, the clinically significant mean changes in their scores on the GIQLI subscales for symptoms, emotions, physical functions, and social function were respectively 6.42, 6.86, 7.64, and 6.46 points. After patients have undergone cholecystectomy, the MCIDs for the GIQLI subscales can play an important role in interpretation of the scores, application of them in clinical practice, and verification of treatment effects.
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References
Bitzer EM, Lorenz C, Nickel S, Dörning H, Trojan A (2008) Assessing patient-reported outcomes of cholecystectomy in short-stay surgery. Surg Endosc 22:2712–2719
Borzellino G, Sauerland S, Minicozzi AM, Verlato G, Di Pietrantonj C, de Manzoni G, Cordiano C (2008) Laparoscopic cholecystectomy for severe acute cholecystitis: a meta-analysis of results. Surg Endosc 22:8–15
Keus F, de Vries J, Gooszen HG, van Laarhoven CJ (2008) Laparoscopic versus small-incision cholecystectomy: health status in a blind randomised trial. Surg Endosc 22:1649–1659
Revicki D, Hays RD, Cella D, Sloan J (2008) Recommended methods for determining responsiveness and minimally important differences for patient-reported outcomes. J Clin Epidemiol 61:102–109
Copay AG, Subach BR, Glassman SD, Polly DW Jr, Schuler TC (2007) Understanding the minimum clinically important difference: a review of concepts and methods. Spine J 7:541–546
Beaton DE, Boers M, Wells GA (2002) Many faces of the minimal clinically important difference (MCID): a literature review and directions for future research. Curr Opin Rheumatol 14:109–114
Crosby RD, Kolotkin RL, Williams GR (2003) Defining clinically meaningful change in health-related quality of life. J Clin Epidemiol 56:395–407
Yeung SM, Shiu AT, Martin CR, Chu KM (2006) Translation and validation of the Chinese version of the Gastrointestinal Quality of Life Index in patients with gastric tumor. J Psychosom Res 61:469–477
Hays RD, Farivar SS, Liu H (2005) Approaches and recommendations for estimating minimally important differences for health-related quality-of-life measures. COPD 2:63–67
Kazis LE, Anderson JJ, Meenan RF (1989) Effect sizes for interpreting changes in health status. Med Care 27:178–189
Sloan JA, Cella D, Hays RD (2005) Clinical significance of patient-reported questionnaire data: another step toward consensus. J Clin Epidemiol 58:1217–1219
Hays RD, Brodsky M, Johnston MF, Spritzer KL, Hui KK (2005) Evaluating the statistical significance of health-related quality-of-life change in individual patients. Eval Health Prof 28:160–171
Husted JA, Cook RJ, Farewell VT, Gladman DD (2000) Methods for assessing responsiveness: a critical review and recommendations. J Clin Epidemiol 53:459–468
Hays RD, Woolley JM (2000) The concept of clinically meaningful difference in health-related quality-of-life research: how meaningful is it? Pharmacoeconomics 18:419–423
Yost KJ, Sorensen MV, Hahn EA, Glendenning GA, Gnanasakthy A, Cella D (2005) Using multiple anchor- and distribution-based estimates to evaluate clinically meaningful change on the Functional Assessment of Cancer Therapy-Biologic Response Modifiers (FACT-BRM) instrument. Value Health 8:117–127
Quintana JM, Arostegui I, Oribe V, López de Tejada I, Barrios B, Garay I (2005) Influence of age and gender on quality-of-life outcomes after cholecystectomy. Qual Life Res 14:815–825
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Shi, HY., Lee, KT., Lee, HH. et al. The minimal clinically important difference in the Gastrointestinal Quality-of-Life Index after cholecystectomy. Surg Endosc 23, 2708–2712 (2009). https://doi.org/10.1007/s00464-009-0475-6
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DOI: https://doi.org/10.1007/s00464-009-0475-6