Skip to main content
Log in

Improved cosmeceutical phototherapy using microneedle

  • Technical Paper
  • Published:
Microsystem Technologies Aims and scope Submit manuscript

Abstract

Skin rejuvenation is the most popular topic in cosmetic industry. Recently, skin phototherapy is spotlighted among a lot of skin therapies by its advantageous effects and ease of use. Phototherapy has been widely used for cosmeceutical purposes such as anti-aging or anti-bacterial effects. By the optical properties of light, however, the visible lights cannot reach deep inside the skin layer by reflection and scattering at the outermost boundary of the skin, the stratum corneum and epidermis. This paper describes new method to improve the skin phototherapy using microneedles. We used microneedle as the light transporter like optic fiber to transport light inside the skin by total internal reflection. The total internal reflection inside microneedles was geometrically analyzed and was measured microscopically. The light transmittance with or without a microneedle array was measured using an optical microscope system. Three different ranges of lights (red, green, blue) were exposed on the backside of the microneedle and the light pass through the microneedles. As the results, using microneedles, light transmissivity was dramatically improved even the shorter wavelength of the light (Blue light). Collaboration of phototherapy and microneedle will be a powerful cosmetic and medical tool for skin therapy.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5

Similar content being viewed by others

References

  • Ammad S, Gonzales M, Edwards C, Finlay AY, Mills C (2008) An assessment of the efficacy of blue light phototherapy in the treatment of acne vulgaris. J cosmet Dermatol 7:180–188

    Article  Google Scholar 

  • Avci P, Gupta A, Sadasivam M, Vecchio D, Pam Z, Pam N, Hamblin MR (2013) Low-level laser (light) therapy (LLLT) in skin: stimulating, healing, restoring. Semin Cutan Med Surg 32(1):41–52

    Google Scholar 

  • Bitter PH (2000) Noninvasive rejuvenation of photodamaged skin using serial, full-face intense pulsed light treatments. Dermatol Surg 26:835–843

    Article  Google Scholar 

  • Chabert R, Fouque L, Pinacolo S, Garcia-Gimenez N, Bonnans M, Cucumel K, Domloge N (2015) Evaluation of light-emitting diodes (LED) effect on skin biology (in vitro study). Skin Res Technol 21:426–436

    Article  Google Scholar 

  • Ding H, Lu JQ, Wooden WA, Kragel PJ, Hu X-H (2006) Refractive indices of human skin tissues at eight wavelengths and estimated dispersion relations between 300 and 1600 nm. Phys Med Biol 51:1479

    Article  Google Scholar 

  • Elman M, Slatkine M, Harth Y (2003) The effective treatment of acne vulgaris by a high-intensity, narrow band 405–420 nm light source. J Cosmet Laser Therapy 5:111–117

    Article  Google Scholar 

  • Gold MH, Goldberg DJ, Nestor MS (2017) Current treatments of acne: medications, lights, lasers, and a novel 650-μs 1064-nm Nd: YAG laser. J Cosmet Dermatol 16:303–318

    Article  Google Scholar 

  • Liebl H, Kloth LC (2012) Skin cell proliferation stimulated by microneedles. J Am Coll Clin Wound Spec 4:2–6

    Article  Google Scholar 

  • Lister T, Wright PA, Chappell PH (2012) Optical properties of human skin. J Biomed Opt 17:090901

    Google Scholar 

  • Mahmoud BH, Hexsel CL, Hamzavi IH, Lim HW (2008) Effects of visible light on the skin. Photochem Photobiol 84:450–462

    Article  Google Scholar 

  • McCrudden MT, McAlister E, Courtenay AJ, González-Vázquez P, Raj Singh TR, Donnelly RF (2015) Microneedle applications in improving skin appearance. Exp Dermatol 24:561–566

    Article  Google Scholar 

  • Mohammed YH et al (2014) Microneedle enhanced delivery of cosmeceutically relevant peptides in human skin. PloS one 9:e101956

    Article  Google Scholar 

  • Mustafa F, Jaafar M (2013) Comparison of wavelength-dependent penetration depths of lasers in different types of skin in photodynamic therapy. Indian J Phys 87:203–209

    Article  Google Scholar 

  • Rohringer S et al (2017) The impact of wavelengths of LED light-therapy on endothelial cells. Sci Rep 7:10700

    Article  Google Scholar 

  • Russell B, Kellett N, Reilly L (2005) A study to determine the efficacy of combination LED light therapy (633 nm and 830 nm) in facial skin rejuvenation. J Cosmet Laser Therapy 7:196–200

    Article  Google Scholar 

  • Sheikholeslami M, Ganji DD (2016a) Heat transfer enhancement in an air to water heat exchanger with discontinuous helical turbulators; experimental and numerical studies. Energy 116:341–352

    Article  Google Scholar 

  • Sheikholeslami M, Ganji DD (2016b) Heat transfer improvement in a double pipe heat exchanger by means of perforated turbulators. Energy Convers Manage 127:112–123

    Article  Google Scholar 

  • Singh A, Yadav S (2016) Microneedling: advances and widening horizons. Indian Dermatol Online Jl 7:244

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Myeongwoo Kang.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kang, M., Shim, C., Na, S. et al. Improved cosmeceutical phototherapy using microneedle. Microsyst Technol 25, 2547–2552 (2019). https://doi.org/10.1007/s00542-018-4248-9

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00542-018-4248-9

Navigation