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A prospective randomized controlled study comparing the pain relief in patients with osteoporotic vertebral compression fractures with the use of vertebroplasty or facet blocking

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Abstract

Purpose

To compare the clinical and radiological outcomes of patients undergoing percutaneous vertebroplasty (PVP) versus those undergoing facet blocking (FB) for severe pain due to osteoporotic vertebral compression fractures (OVCFs).

Methods

Two hundred and six patients who had OVCFs on spine radiography and intractable back pain for ≤8 weeks were recruited between January 2009 and January 2013 (165 females and 41 males, age ≥55 years). Patients were randomly assigned to the PVP group (100 patients) or the FB group (106 patients). VAS, ODI, Roland Morris disability (RMD) scores, scores on the Standardized Physical Component of the SF-36 form (SPC) and scores on the Standardized Mental Component of the SF-36 form (SMC) were determined preoperatively and at each follow-up time (1 day, 1 week, 1, 3, 6, and 12 months). In addition, plain radiographs were obtained at 3, 6, and 12 months postoperatively to detect new fractures.

Results

Significantly lower VAS, ODI, and RMD scores for patients in the PVP group compared to those in the FB group were observed at follow-up of 1 day and 1 week (p < 0.05). However, differences in the VAS, ODI, RMD and SPC/MCS (SF-36) scores between the two groups at follow-ups of more than 1 month were statistically insignificant (p > 0.05). Difference in numbers of new fractures in the two groups at the follow-up of 12 months was also statistically insignificant.

Conclusions

PVP produced better pain relief than FB in the short term (≤1 week). However, the difference in pain-relief between these two techniques was insignificant in the long term (follow-up between 1 month and 12 months).

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Authors and Affiliations

  1. Department of Spine Surgery, Honghui Hospital, Xi’an Jiaotong University College of Medicine, No. 76 Nanguo Road, Xi’an, 710054, Shanxi, China

    Biao Wang, Hua Guo, Li Yuan, Dageng Huang, Haiping Zhang & Dingjun Hao

Authors
  1. Biao Wang
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  2. Hua Guo
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  3. Li Yuan
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  4. Dageng Huang
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  5. Haiping Zhang
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  6. Dingjun Hao
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Correspondence to Dingjun Hao.

Ethics declarations

The device(s)/drug(s) is/are FDA approved or approved by corresponding national agency for this indication. No funds were received in support of this work. No benefits in any form have been or will be received from a commercial party related directly or indirectly to the subject of this manuscript. No financial assistance was provided to any of the authors involved in the production of this paper.

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None of the authors has any potential conflict of interest.

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Wang, B., Guo, H., Yuan, L. et al. A prospective randomized controlled study comparing the pain relief in patients with osteoporotic vertebral compression fractures with the use of vertebroplasty or facet blocking. Eur Spine J 25, 3486–3494 (2016). https://doi.org/10.1007/s00586-016-4425-4

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  • DOI: https://doi.org/10.1007/s00586-016-4425-4

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