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Genetic aspects in attention-deficit/hyperactivity disorder

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Summary

Attention-deficit/hyperactivity disorder (ADHD) is a common psychiatric disorder among children and adolescents with high heritability. Molecular genetic findings support the thesis that dopaminergic, serotonergic, and noradrenergic neurotransmission pathways account for the etiology of this complex disease. Genetic research comprises formal genetic studies, candidate gene studies, linkage analyses, and recently large-scale genome wide association studies, gene-environement interaction studies, and pharmacogenetics. This article comprehensively reviews the latest findings on the genetics of ADHD.

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Authors and Affiliations

  1. Department of Child and Adolescent Psychiatry, Rheinische Kliniken Essen, University of Duisburg-Essen, Essen, Germany

    Ö. Albayrak, S. Friedel, B. G. Schimmelmann, A. Hinney & J. Hebebrand

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  1. Ö. Albayrak
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  2. S. Friedel
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  3. B. G. Schimmelmann
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  4. A. Hinney
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  5. J. Hebebrand
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Correspondence to Ö. Albayrak.

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Correspondence: Özgür Albayrak, Department of Child and Adolescent Psychiatry, Rheinische Kliniken Essen, University of Duisburg-Essen, Virchowstr. 174, 45147 Essen, Germany

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Albayrak, Ö., Friedel, S., Schimmelmann, B. et al. Genetic aspects in attention-deficit/hyperactivity disorder. J Neural Transm 115, 305–315 (2008). https://doi.org/10.1007/s00702-007-0839-9

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