Zusammenfassung
Hintergrund
Entscheidend für den Erfolg der Strahlentherapie ist die zeitgerechte Applikation ohne toxizitätsbedingte Pausen; eine effektive Supportivtherapie ist obligat.
Fragestellung
Es werden Prophylaxe und Therapie akuter/subakuter Strahlenfolgen beschrieben.
Methoden
Von 1995 bis 2011 publizierte Studien wurden systematisch analysiert und die Leitlinie „Supportive Maßnahmen der Radioonkologie“ der Deutschen Gesellschaft für Radioonkologie erstellt.
Ergebnisse
Prophylaxe und Therapie der (sub)akuten Strahlenreaktion werden für Bestrahlungen des Zerebrums, im Kopf-Hals-Bereich, der Lunge und der Haut dargestellt.
Schlussfolgerung
Strahlentherapiepausen können durch leitliniengerechte Supportivtherapie vermieden werden. Bei Verdacht auf Nebenwirkungen sollten die Patienten in der Radioonkologie vorgestellt werden.
Abstract
Background
Radiotherapy is effective if applied in a timely manner. Supportive therapy is necessary to avoid toxicity-related treatment interruptions.
Objective
To describe evidence-based supportive therapy in radiation oncology.
Methoden
Studies published in 1995–2011 were systematically analyzed and guidelines were defined.
Results
The prevention and therapy of (sub)acute radiation side effects of the cerebrum, head and neck region, skin and lungs are described.
Conclusion
Guideline conform supportive therapy mitigates side effects and avoids interruptions in radiation therapy. Patients with suspected radiation side effects should present to a radiation oncology department.
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Interessenkonflikt. Keiner der Autoren hat einen Interessenkonflikt. Der Beitrag enthält keine Studien an Menschen oder Tieren.
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Höller, U., Schubert, T. Supportive Therapie in der Radioonkologie. Onkologe 21, 318–322 (2015). https://doi.org/10.1007/s00761-014-2797-9
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DOI: https://doi.org/10.1007/s00761-014-2797-9