Abstract
Introduction
Lymphangiomas are relatively uncommon head and neck region lymphatic malformations. Although surgery can be still considered the mainstay of treatment, sclerotherapy by OK-432 is becoming a widespread treatment option. The aim of this article is to present and discuss the management and outcomes of a series of cases of lymphangiomas.
Methods
All patients with lymphangiomas who were treated from 2010 to 2018 were reviewed. The following data were recorded: age, gender, subtype, staging, type of treatment, outcome, and recurrence.
Results
Fifteen patients (9 females, 6 males) were included with 2 microcystic and 13 macrocystic lymphangiomas. Six patients underwent surgery with excision (5 with a complete success, one with a fair success), whereas the remaining 9 subjects underwent sclerotherapy by OK-432 (6 with a complete success, 3 with a fair success). No postoperative complications were observed.
Conclusions
All modes of treatment are important in properly selected patients affected by lymphangiomas. OK-432 therapy is a safe and effective option in the treatment of head and neck lymphangiomas.
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References
Balakrishnan K, Perkins J (2012) Management of head and neck lymphatic malformations. Facial Plast Surg 28:596–602
Efe N, Altas E, Mazlumoglu MR, Aktan B, Ucuncu H, Eren S, Oner F (2016) Excellent result with the use of single-dose OK-432 in cervical macrocystic lymphangioma. J Craniofac Surg 27:1802–1803
Gilony D, Schwartz M, Shpitzer T, Feinmesser R, Kornreich L, Raveh E (2012) Treatment of lymphatic malformations: a more conservative approach. J Pediatr Surg 47:1837–1842
Hamoir M, Plouin-Gaudon I, Rombaux P, Francois G, Cornu AS, Desuter G, Clapuyt P, Debauche C, Verellen G, Beguin C (2001) Lymphatic malformations of the head and neck: a retrospective review and a support for staging. Head Neck 23:326–337
Lerat J, Mounayer C, Scomparin A, Orsel S, Bessede JP, Aubry K (2016) Head and neck lymphatic malformation and treatment: clinical study of 23 cases. Eur Ann Otorhinolaryngol Head Neck Dis 133:393–396
Mitsukawa N, Satoh K (2012) New treatment for cystic lymphangiomas of the face and neck: cyst wall rupture and cyst aspiration combined with sclerotherapy. J Craniofac Surg. 23:1117–1119
Ohta N, Fukase S, Watanabe T, Ito T, Aoyagi M (2010) Effects and mechanism of OK-432 therapy in various neck cystic lesions. Acta Otolaryngol 130:1287–1292
Golinelli G, Toso A, Borello G, Aluffi P, Pia F (2015) Percutaneous sclerotherapy with OK-432 of a cervicomediastinal lymphangioma. Ann Thorac Surg 100:1879–1881
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Aluffi Valletti, P., Brucoli, M., Boffano, P. et al. A single-center experience in the management of head and neck lymphangiomas. Oral Maxillofac Surg 24, 109–115 (2020). https://doi.org/10.1007/s10006-020-00832-z
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DOI: https://doi.org/10.1007/s10006-020-00832-z